Evidence map›Paper›PMID 29555959›Full record

ArticleScientific reports2018

Waist circumference is a mediator of dietary pattern in Non-alcoholic fatty liver disease.

Alireza Ghaemi, Narjes Hosseini, Saeed Osati, Mohammad Mehdi Naghizadeh, Azizallah Dehghan, Elham Ehrampoush, Behnam Honarvar, Reza Homayounfar

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Alireza GhaemiDepartment of Basic Sciences and Nutrition, Health Sciences Research Center, Faculty of public Health, Mazandaran University of Medical Sciences, Sari, Iran.
Narjes HosseiniStudent Research Committee, Fasa University of Medical Sciences, Fasa, Iran.
Saeed OsatiNational Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mohammad Mehdi NaghizadehNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
Azizallah DehghanNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
Elham EhrampoushNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
Behnam HonarvarHealth Policy Research Center, Institute of Health, Shiraz University of Medical Science, Shiraz, Iran.
Reza HomayounfarNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran. r_homayounfar@yahoo.com.ORCID 0000-0001-5398-9519
Fasa University of Medical Sciences · IRShiraz University · IRMazandaran University of Medical Sciences · IRNational Nutrition and Food Technology Research Institute · IRShiraz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-alcoholic fatty liver disease (NAFLD) is an example of pathological fat accumulation in the liver and one of the major health conditions in the world. This study aimed to examine the independent role of dietary patterns in the development of NAFLD. In a cross-sectional study, 1500 individuals referred to a nutrition clinic were randomly selected, their demographic, anthropometric and blood metabolic indices were obtained, and food frequency questionnaires were completed for them. Liver stiffness was calculated using the NAFLD score formula and fibroscan. The two dominant dietary patterns identified were the "healthy" and "unhealthy dietary patterns". A significant percentage of those with NAFLD (45%) were in the upper quartile of the unhealthy model; however, only 10% had the healthy pattern (p < 0.001). In this study, 32.9 and 13.9% of the healthy and unhealthy participants were in the upper quartile of the healthy diet pattern. Also, it was shown that waist circumference is a strong mediator of dietary patterns and NAFLD relationship, and the indirect effect of diet through abdominal circumference is 28 times greater than the direct effect on NAFLD. The results suggested that healthy and unhealthy dietary patterns are respectively associated with lower- and higher-risk of NAFLD but the role of waist circumference as a mediator deserves more consideration.

Indexed as

DietWaist CircumferenceAdultDiet, HealthyFemaleHumansMaleNon-alcoholic Fatty Liver Disease

Identifiers

PMID29555959
PMCPMC5859081
OpenAlexW2791156912

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.