Evidence map›Paper›PMID 29555843›Full record

ArticleThe Biochemical journal2018

RNase I regulates

Benjamin M Fontaine, Kevin S Martin, Jennifer M Garcia-Rodriguez, Claire Jung, Laura Briggs, Jessica E Southwell, Xin Jia, Emily E Weinert

Open access · greenAbstract read
In one paragraph

Article in The Biochemical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. At the Crossroad of Nucleotide Dynamics and Protein Synthesis in Bacteria.Microbiology and molecular biology reviews : MMBR · 2023
    Review
  8. Genomic Distribution of Pro-VirulentInternational journal of molecular sciences · 2023
    Article
  9. Review
  10. An OFrontiers in microbiology · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Trans-acting regulators of ribonuclease activity.Journal of microbiology (Seoul, Korea) · 2021
    Review
  17. Molecular Dissection ofInternational journal of molecular sciences · 2021
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Benjamin M FontaineDepartment of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, GA 30322, U.S.A.
Kevin S MartinDepartment of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, GA 30322, U.S.A.
Jennifer M Garcia-RodriguezDepartment of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, GA 30322, U.S.A.
Claire JungDepartment of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, GA 30322, U.S.A.
Laura BriggsDepartment of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, GA 30322, U.S.A.
Jessica E SouthwellDepartment of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, GA 30322, U.S.A.
Xin JiaDepartment of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, GA 30322, U.S.A.
Emily E WeinertDepartment of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, GA 30322, U.S.A. emily.weinert@emory.edu.ORCID 0000-0002-4986-8682
Emory University · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
UPR-Humacao Maximizing Access to Research Careers Undergraduate Student Training in Academic Research ProgramT34GM008156 · NIGMS · UNIVERSITY OF PUERTO RICO AT HUMACAO · PI TRAVERSO, EDWIN E, VEGA-BERMUDEZ, ESTHER Z · 1986 to 2021
$5.4M
Probing the Metabolism and Cellular Roles of 2',3'-Cyclic Nucleotide MonophosphateR01GM125842 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI WEINERT, EMILY E · 2018 to 2022
$1.6M
NCATS NIH HHS UL1 TR000454NCATS NIH HHS UL1 TR002378NIGMS NIH HHS R01 GM125842NIGMS NIH HHS T34 GM008156
6 · The paper itself

Abstract

Regulation of nucleotide and nucleoside concentrations is critical for faithful DNA replication, transcription, and translation in all organisms, and has been linked to bacterial biofilm formation. Unusual 2',3'-cyclic nucleotide monophosphates (2',3'-cNMPs) recently were quantified in mammalian systems, and previous reports have linked these nucleotides to cellular stress and damage in eukaryotes, suggesting an intriguing connection with nucleotide/nucleoside pools and/or cyclic nucleotide signaling. This work reports the first quantification of 2',3'-cNMPs in

Indexed as

BiofilmsEscherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialNucleotides, CyclicRibonuclease, PancreaticRNA, BacterialRNA, MessengerRNA StabilitySignal TransductionEscherichia coli ProteinsNucleotides, CyclicRibonuclease, PancreaticRNA, BacterialRNA, Messengerbiofilmcyclic nucleotidemRNA degradationRNase I

Identifiers

PMID29555843
PMCPMC6452634
OpenAlexW2789600674

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.