Evidence map›Paper›PMID 29555770›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Converting

Antonella Caforio, Melvin F Siliakus, Marten Exterkate, Samta Jain, Varsha R Jumde, Ruben L H Andringa, Servé W M Kengen, Adriaan J Minnaard, Arnold J M Driessen, John van der Oost

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 102 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Synthetic Lipid Biology.Chemical reviews · 2025
    Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Optimizing Archaeal Lipid Biosynthesis inACS synthetic biology · 2024
    Article
  19. Isoprenoid CARTs:Biomacromolecules · 2024
    Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Antonella CaforioDepartment of Molecular Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 9747 AG Groningen, The Netherlands.
Melvin F SiliakusLaboratory of Microbiology, Wageningen University & Research, 6708 WE Wageningen, The Netherlands.
Marten ExterkateDepartment of Molecular Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 9747 AG Groningen, The Netherlands.
Samta JainDepartment of Molecular Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 9747 AG Groningen, The Netherlands.
Varsha R JumdeStratingh Institute for Chemistry, University of Groningen, 9747 AG Groningen, The Netherlands.
Ruben L H AndringaStratingh Institute for Chemistry, University of Groningen, 9747 AG Groningen, The Netherlands.
Servé W M KengenLaboratory of Microbiology, Wageningen University & Research, 6708 WE Wageningen, The Netherlands.
Adriaan J MinnaardStratingh Institute for Chemistry, University of Groningen, 9747 AG Groningen, The Netherlands.
Arnold J M DriessenDepartment of Molecular Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 9747 AG Groningen, The Netherlands; a.j.m.driessen@rug.nl john.vanderoost@wur.nl.
John van der OostLaboratory of Microbiology, Wageningen University & Research, 6708 WE Wageningen, The Netherlands; a.j.m.driessen@rug.nl john.vanderoost@wur.nl.
University of Groningen · NLWageningen University & Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the main differences between bacteria and archaea concerns their membrane composition. Whereas bacterial membranes are made up of glycerol-3-phosphate ester lipids, archaeal membranes are composed of glycerol-1-phosphate ether lipids. Here, we report the construction of a stable hybrid heterochiral membrane through lipid engineering of the bacterium

Indexed as

Biological EvolutionArchaeaCell MembraneEscherichia coliEthersMembrane LipidsPhospholipidsEthersMembrane LipidsPhospholipidsarchaeabacteriaether lipidshybrid membraneslipid biosynthesis

Identifiers

PMID29555770
PMCPMC5889666
OpenAlexW2789784701

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.