Evidence map›Paper›PMID 29555759›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Construction and evolution of an

Paul P Lin, Alec J Jaeger, Tung-Yun Wu, Sharon C Xu, Abraxa S Lee, Fanke Gao, Po-Wei Chen, James C Liao

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 110 citations in OpenAlex.

  1. Coordinating Calvin Cycle and Glycolysis inACS synthetic biology · 2026
    Article
  2. The return of metabolism: biochemistry and physiology of glycolysis.Biological reviews of the Cambridge Philosophical Society · 2026
    Review
  3. Article
  4. New-to-nature CONature communications · 2024
    Article
  5. Article
  6. Article
  7. Multidimensional Optimization ofBiodesign research · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Cofactor Metabolic Engineering ofBioengineering (Basel, Switzerland) · 2023
    Article
  13. Constructing Nanocaged Enzymes for Synergistic Catalysis of COAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Frontiers in bioengineering and biotechnology · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Paul P LinDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095.
Alec J JaegerDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095.
Tung-Yun WuDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095.
Sharon C XuDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095.
Abraxa S LeeDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095.
Fanke GaoDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095.
Po-Wei ChenDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095.
James C LiaoInstitute of Biological Chemistry, Academia Sinica, 115 Taipei, Taiwan liaoj@gate.sinica.edu.tw.
University of California, Los Angeles · USInstitute of Biological Chemistry, Academia Sinica · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Embden-Meyerhoff-Parnas (EMP) pathway, commonly known as glycolysis, represents the fundamental biochemical infrastructure for sugar catabolism in almost all organisms, as it provides key components for biosynthesis, energy metabolism, and global regulation. EMP-based metabolism synthesizes three-carbon (C3) metabolites before two-carbon (C2) metabolites and must emit one CO

Indexed as

GlycolysisMetabolic EngineeringAcetyl Coenzyme ACarbohydrate MetabolismEnergy MetabolismEscherichia coliFermentationGlucoseMutationAcetyl Coenzyme AGlucoseEscherichia colievolutionglycolysismetabolic engineeringsynthetic biology

Identifiers

PMID29555759
PMCPMC5889684
OpenAlexW2799985031

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.