Evidence map›Paper›PMID 29555746›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

mTOR signaling in VIP neurons regulates circadian clock synchrony and olfaction.

Dong Liu, Adam Stowie, Nuria de Zavalia, Tanya Leise, Salil Saurav Pathak, Lester R Drewes, Alec J Davidson, Shimon Amir, Nahum Sonenberg, Ruifeng Cao

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 43 citations in OpenAlex.

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  4. Control of Selective mRNA Translation in Neuronal Subcellular Compartments in Health and Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
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  19. Article
  20. From clock to functional pacemaker.The European journal of neuroscience · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Dong LiuDepartment of Biomedical Sciences, University of Minnesota Medical School, Duluth, MN 55812.
Adam StowieDepartment of Neurobiology, Morehouse School of Medicine, Atlanta, GA 30310.
Nuria de ZavaliaCenter for Studies in Behavioral Neurobiology, Concordia University, Montreal, QC H4B 1R6, Canada.
Tanya LeiseDepartment of Mathematics and Statistics, Amherst College, Amherst, MA 01002.
Salil Saurav PathakDepartment of Biomedical Sciences, University of Minnesota Medical School, Duluth, MN 55812.
Lester R DrewesDepartment of Biomedical Sciences, University of Minnesota Medical School, Duluth, MN 55812.
Alec J DavidsonDepartment of Neurobiology, Morehouse School of Medicine, Atlanta, GA 30310.
Shimon AmirCenter for Studies in Behavioral Neurobiology, Concordia University, Montreal, QC H4B 1R6, Canada; shimon.amir@concordia.ca nahum.sonenberg@mcgill.ca rcao@umn.edu.
Nahum SonenbergDepartment of Biochemistry, McGill University, Montreal, QC H3A 1A3, Canada; shimon.amir@concordia.ca nahum.sonenberg@mcgill.ca rcao@umn.edu.
Ruifeng CaoDepartment of Biomedical Sciences, University of Minnesota Medical School, Duluth, MN 55812; shimon.amir@concordia.ca nahum.sonenberg@mcgill.ca rcao@umn.edu.ORCID 0000-0001-5105-7726
University of Minnesota, Duluth · USConcordia University · CAMorehouse School of Medicine · USAmherst College · USMcGill University · CA

Funding

Novel mechanisms of immunological priming after circadian disruptionSC1GM112567 · NIGMS · MOREHOUSE SCHOOL OF MEDICINE · PI DAVIDSON, ALEC J · 2015 to 2018
$1.4M
CIHR MOP142458CIHR MOP7214Howard Hughes Medical InstituteNIGMS NIH HHS SC1 GM112567
6 · The paper itself

Abstract

Mammalian/mechanistic target of rapamycin (mTOR) signaling controls cell growth, proliferation, and metabolism in dividing cells. Less is known regarding its function in postmitotic neurons in the adult brain. Here we created a conditional

Indexed as

AnimalsCircadian RhythmMiceMice, KnockoutNeuronsOlfactory BulbOlfactory PathwaysSignal TransductionSuprachiasmatic NucleusTOR Serine-Threonine KinasesVasoactive Intestinal PeptidemTOR protein, mouseTOR Serine-Threonine KinasesVasoactive Intestinal Peptidecircadian clockmTORolfactionSCNVIP

Identifiers

PMID29555746
PMCPMC5889665
OpenAlexW2790842764

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.