Evidence map›Paper›PMID 29555693›Full record

ArticleJournal of bacteriology2018

D-fining DarR: a LysR-type transcriptional regulator that responds to D-aspartate.

Mark J Mandel

Abstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Mark J MandelDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI USA mmandel@wisc.edu.

Funding

Genetic Analysis of Beneficial Bacterial ColonizationR35GM119627 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI MANDEL, MARK J · 2016 to 2021
$2.2M
Regulation of Bacterial Aggregation During Host ColonizationR21AI117262 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI MANDEL, MARK J · 2016 to 2017
$408k
NIAID NIH HHS R21 AI117262NIGMS NIH HHS R35 GM119627
6 · The paper itself

Abstract

Work from Jones, Stabb, et al. describes a D-aspartate sensing system in Proteobacteria. D-amino acids are critical components of peptidoglycan and other structures. The new study identifies the LysR-type transcriptional regulator, DarR, which activates the aspartate racemase RacD. Overexpression of RacD enables it to synthesize D-glutamate and restore normal peptidoglycan in a

Identifiers

PMID29555693
PMCPMC6040187

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.