ArticleCirculation. Genomic and precision medicine2018
Epigenetic Age Acceleration: A Biological Doomsday Clock for Cardiovascular Disease?
Article in Circulation. Genomic and precision medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Population epigenetics: deciphering DNA methylation diversity and its implications for health, disease, and evolution.Molecular biology and evolution · 2026Review
- Epigenetic aging markers in the association between frailty and mortality among U.S. adults.BMC medicine · 2026Article
- Histone modification clocks for robust cross-species biological age prediction and elucidating senescence regulation.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Social genomics and cancer - untangling nature from nurture in squamous cell carcinoma outcomes.Frontiers in oncology · 2026Review
- Gestational phthalate levels and biomarkers of aging in infants and children from New York City.Environmental research · 2025Article
- Depression, Subjective Health, Obesity, and Multimorbidity are Associated with Epigenetic Age Acceleration.Journal of biomedical and life sciences · 2025Article
- Neighborhood Stressors and Epigenetic Age Acceleration Among Older Americans.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Article
- Gut microbiota and epigenetic age acceleration: a bi-directional Mendelian randomization study.Aging clinical and experimental research · 2024Article
- Molecular signaling and clinical implications in the human aging-cancer cycle.Seminars in cancer biology · 2024Review
- Article
- EchoAGE: Echocardiography-based Neural Network Model Forecasting Heart Biological Age.Aging and disease · 2024Article
- Neighborhood Environment and Epigenetic Age: A Scoping Review.Western journal of nursing research · 2023Article
- Article
- Within subject cross-tissue analyzes of epigenetic clocks in substance use disorder postmortem brain and blood.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2023Article
- Digital methylation assessments of alcohol and cigarette consumption account for common variance in accelerated epigenetic ageing.Epigenetics · 2022Article
- The Achilles' heel of cancer survivors: fundamentals of accelerated cellular senescence.The Journal of clinical investigation · 2022Review
- Evaluation of epigenetic age calculators between preeclampsia and normotensive pregnancies in an Australian cohort.Scientific reports · 2022Observational
- Maternal biological age assessed in early pregnancy is associated with gestational age at birth.Scientific reports · 2021Article
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Abstract
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.