Evidence map›Paper›PMID 29555665›Full record

Trial reportHypertension (Dallas, Tex. : 1979)2018

Relationship of Sodium Intake and Blood Pressure Varies With Energy Intake: Secondary Analysis of the DASH (Dietary Approaches to Stop Hypertension)-Sodium Trial.

Maureen A Murtaugh, Jeannette M Beasley, Lawrence J Appel, Patricia M Guenther, Molly McFadden, Tom Greene, Janet A Tooze

Abstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Hypertension (Dallas, Tex. : 1979), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
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  7. Article
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  11. Review
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  14. Article
  15. Benefits of Mediterranean and Japanese Diets among Nurses: A Scoping Literature Review.Endocrine, metabolic & immune disorders drug targets · 2024
    Article
  16. Article
  17. The damaging duo: Obesity and excess dietary salt contribute to hypertension and cardiovascular disease.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023
    Review
  18. Salt Taste and Salt Sensitive Hypertension in HIV.Current hypertension reports · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maureen A MurtaughFrom the Division of Epidemiology, Department of Medicine (M.A.M., T.G., M.M.) and Department of Nutrition and Integrative Physiology (P.M.G.), University of Utah, Salt Lake City; Department of Medicine, New York University School of Medicine (J.M.B.); Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, MD (L.J.A.); and Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC (J.A.T.). Maureen.Murtaugh@hsc.utah.edu.
Jeannette M BeasleyFrom the Division of Epidemiology, Department of Medicine (M.A.M., T.G., M.M.) and Department of Nutrition and Integrative Physiology (P.M.G.), University of Utah, Salt Lake City; Department of Medicine, New York University School of Medicine (J.M.B.); Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, MD (L.J.A.); and Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC (J.A.T.).
Lawrence J AppelFrom the Division of Epidemiology, Department of Medicine (M.A.M., T.G., M.M.) and Department of Nutrition and Integrative Physiology (P.M.G.), University of Utah, Salt Lake City; Department of Medicine, New York University School of Medicine (J.M.B.); Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, MD (L.J.A.); and Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC (J.A.T.).
Patricia M GuentherFrom the Division of Epidemiology, Department of Medicine (M.A.M., T.G., M.M.) and Department of Nutrition and Integrative Physiology (P.M.G.), University of Utah, Salt Lake City; Department of Medicine, New York University School of Medicine (J.M.B.); Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, MD (L.J.A.); and Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC (J.A.T.).
Molly McFaddenFrom the Division of Epidemiology, Department of Medicine (M.A.M., T.G., M.M.) and Department of Nutrition and Integrative Physiology (P.M.G.), University of Utah, Salt Lake City; Department of Medicine, New York University School of Medicine (J.M.B.); Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, MD (L.J.A.); and Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC (J.A.T.).
Tom GreeneFrom the Division of Epidemiology, Department of Medicine (M.A.M., T.G., M.M.) and Department of Nutrition and Integrative Physiology (P.M.G.), University of Utah, Salt Lake City; Department of Medicine, New York University School of Medicine (J.M.B.); Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, MD (L.J.A.); and Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC (J.A.T.).
Janet A ToozeFrom the Division of Epidemiology, Department of Medicine (M.A.M., T.G., M.M.) and Department of Nutrition and Integrative Physiology (P.M.G.), University of Utah, Salt Lake City; Department of Medicine, New York University School of Medicine (J.M.B.); Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, MD (L.J.A.); and Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC (J.A.T.).

Funding

Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
University of Utah Center for Clinical and Translational ScienceUL1TR001067 · NCATS · UNIVERSITY OF UTAH · PI DERE, WILLARD H., HESS, RACHEL · 2013 to 2017
$19.8M
Untangling Sodium, Energy, and Blood Pressure in Whites and African AmericansR21HL128958 · NHLBI · UNIVERSITY OF UTAH · PI GUENTHER, PATRICIA MAXINE, MURTAUGH, MAUREEN A · 2015 to 2016
$257k
NCATS NIH HHS UL1 TR001067NCATS NIH HHS UL1 TR002538NHLBI NIH HHS R21 HL128958
6 · The paper itself

Abstract

Dietary Na recommendations are expressed as absolute amounts (mg/d) rather than as Na density (mg/kcal). Our objective was to determine whether the strength of the relationship of Na intake with blood pressure (BP) varied with energy intake. The DASH (Dietary Approaches to Stop Hypertension)-Sodium trial was a randomized feeding trial comparing 2 diets (DASH and control) and 3 levels of Na density. Participants with pre- or stage 1 hypertension consumed diets for 30 days in random order; energy intake was controlled to maintain body weight. This secondary analysis of 379 non-Hispanic black and white participants used mixed-effects models to assess the association of Na and energy intakes with BP. The relationships between absolute Na and both systolic and diastolic BP varied with energy intake. BP rose more steeply with increasing Na at lower energy intake than at higher energy intake (

Indexed as

Energy IntakeAdultAnalysis of VarianceBlood Pressure DeterminationCross-Over StudiesDietary Approaches To Stop HypertensionDiet, Sodium-RestrictedFollow-Up StudiesHumansHypertensionMiddle AgedPatient ComplianceReference ValuesRisk AssessmentSodium, DietaryTreatment OutcomeSodium, Dietaryblood pressurebody weightdietenergy intakehypertensionsodium

Identifiers

PMID29555665
PMCPMC5897169

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.