Evidence map›Paper›PMID 29555634›Full record

ArticleAntimicrobial agents and chemotherapy2018

Overcoming the Resistance Hurdle: Pharmacokinetic-Pharmacodynamic Target Attainment Analyses for Rezafungin (CD101) against Candida albicans and Candida glabrata.

Justin C Bader, Elizabeth A Lakota, Shawn Flanagan, Voon Ong, Taylor Sandison, Christopher M Rubino, Sujata M Bhavnani, Paul G Ambrose

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 44 citations in OpenAlex.

  1. Outcomes byAntimicrobial agents and chemotherapy · 2024
    Trial
  2. Invasive Candidiasis in the Intensive Care Unit: Where Are We Now?Journal of fungi (Basel, Switzerland) · 2025
    Review
  3. Activity of Rezafungin Against Echinocandin Non-wild typeOpen forum infectious diseases · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Antifungal Resistance and the Role of New Therapeutic Agents.Current infectious disease reports · 2022
    Review
  14. Article
  15. Article
  16. Antifungal Pipeline.Frontiers in cellular and infection microbiology · 2021
    Review
  17. Emerging of Fatal Colitis with Multidrug-ResistantCase reports in transplantation · 2021
    Article
  18. Review
  19. Article
  20. RezafunginAntimicrobial agents and chemotherapy · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Justin C BaderInstitute for Clinical Pharmacodynamics, Inc., Schenectady, New York, USA jbader@icpd.com.
Elizabeth A LakotaInstitute for Clinical Pharmacodynamics, Inc., Schenectady, New York, USA.
Shawn FlanaganCidara Therapeutics, San Diego, California, USA.
Voon OngCidara Therapeutics, San Diego, California, USA.
Taylor SandisonCidara Therapeutics, San Diego, California, USA.
Christopher M RubinoInstitute for Clinical Pharmacodynamics, Inc., Schenectady, New York, USA.
Sujata M BhavnaniInstitute for Clinical Pharmacodynamics, Inc., Schenectady, New York, USA.
Paul G AmbroseInstitute for Clinical Pharmacodynamics, Inc., Schenectady, New York, USA.
Institute for Clinical Pharmacodynamics (United States) · USCidara Therapeutics (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rezafungin (CD101) is a novel echinocandin antifungal agent with activity against

Indexed as

Antifungal AgentsCandida albicansCandida glabrataCandidemiaCandidiasisDrug Administration ScheduleEchinocandinsHumansMicrobial Sensitivity TestsMonte Carlo MethodAntifungal AgentsEchinocandinsRezafunginCandida albicansCandida glabrataCandida speciesechinocandinPK-PD target attainment

Identifiers

PMID29555634
PMCPMC5971579
OpenAlexW2790911203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.