Evidence map›Paper›PMID 29555582›Full record

ArticleBiochimica et biophysica acta. Gene regulatory mechanisms2018

Suberanilohydroxamic acid prevents TGF-β1-induced COX-2 repression in human lung fibroblasts post-transcriptionally by TIA-1 downregulation.

Alice Pasini, Oliver J Brand, Gisli Jenkins, Alan J Knox, Linhua Pang

Open access · hybridAbstract read
In one paragraph

Article in Biochimica et biophysica acta. Gene regulatory mechanisms, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. O-GlcNAc regulates anti-fibrotic genes in lung fibroblasts through EZH2.Journal of cellular and molecular medicine · 2024
    Article
  3. Article
  4. Jinlian Xiaodu Decoction Protects against Bleomycin-Induced Pulmonary Fibrosis in Rats.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. More than a Genetic Code: Epigenetics of Lung Fibrosis.Molecular diagnosis & therapy · 2020
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Alice PasiniDivision of Respiratory Medicine, University of Nottingham School of Medicine, City Hospital, Nottingham NG5 1PB, United Kingdom; Department of Electrical, Electronic and Information Engineering "Guglielmo Marconi" (DEI), University of Bologna, Via Venezia 52, 47521 Cesena, FC, Italy.
Oliver J BrandDivision of Respiratory Medicine, University of Nottingham School of Medicine, City Hospital, Nottingham NG5 1PB, United Kingdom.
Gisli JenkinsDivision of Respiratory Medicine, University of Nottingham School of Medicine, City Hospital, Nottingham NG5 1PB, United Kingdom.
Alan J KnoxDivision of Respiratory Medicine, University of Nottingham School of Medicine, City Hospital, Nottingham NG5 1PB, United Kingdom.
Linhua PangDivision of Respiratory Medicine, University of Nottingham School of Medicine, City Hospital, Nottingham NG5 1PB, United Kingdom. Electronic address: linhua.pang@nottingham.ac.uk.
Nottingham City Hospital · GBUniversity of Nottingham · GB

Funding

Medical Research Council MR/K003259/1Medical Research Council MR/N005953/1
6 · The paper itself

Abstract

Cyclooxygenase-2 (COX-2), with its main antifibrotic metabolite PGE ABBREVIATIONS:

Indexed as

AdenosineAzacitidineCell LineCyclooxygenase 1Cyclooxygenase 2DecitabineDNA MethylationEnhancer of Zeste Homolog 2 ProteinFibroblastsGene Expression RegulationHistone Deacetylase InhibitorsHumansHydroxamic AcidsLungPromoter Regions, GeneticT-Cell Intracellular Antigen-13-deazaneplanocinAdenosineAzacitidineCyclooxygenase 1Cyclooxygenase 2DecitabineEnhancer of Zeste Homolog 2 ProteinEZH2 protein, humanHistone Deacetylase InhibitorsHydroxamic AcidsPTGS1 protein, humanPTGS2 protein, humanT-Cell Intracellular Antigen-1TGFB1 protein, humanTIA1 protein, humanTransforming Growth Factor beta1VorinostatCyclooxygenase 2 (COX-2)Histone deacetylase inhibitorPost-transcriptional regulation, epigeneticsPulmonary fibrosisTransforming growth factor β1 (TGF-β1)

Identifiers

PMID29555582
PMCPMC5910054
OpenAlexW2791017043

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.