ArticleAmerican journal of ophthalmology2018
Family History in the Primary Open-Angle African American Glaucoma Genetics Study Cohort.
Article in American journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Plasma lipid levels and risk of primary open angle glaucoma: a genetic study using Mendelian randomization.BMC ophthalmology · 2020Pooled it
- Do motivational cards really benefit sibling screening of primary open-angle glaucoma probands?Indian journal of ophthalmology · 2022Trial
- Risk stratification of visual field progression in optic disc drusen with and without glaucoma.International ophthalmology · 2026Article
- Primary Open-Angle Glaucoma among Black and Latinx Populations: Exploring Racial Disparities in the United States.Journal of racial and ethnic health disparities · 2026Review
- Epidemiology and risk factors of glaucoma in a comprehensive health screening baseline report from the Gangnam Eye Cohort Study.Scientific reports · 2025Article
- Exploring Glaucoma: From Pathogenesis to Emerging Diagnostic and Management Strategies.Journal of ophthalmology · 2025Review
- Integrating Deep Learning with Electronic Health Records for Early Glaucoma Detection: A Multi-Dimensional Machine Learning Approach.Bioengineering (Basel, Switzerland) · 2024Article
- Article
- Risk factors for structural and functional progression of primary open-angle glaucoma in an African ancestry cohort.BMJ open ophthalmology · 2023Article
- Clinical and demographic profile of patients less than 40 years of age presenting to glaucoma services at a tertiary care eye hospital in South India.Indian journal of ophthalmology · 2022Article
- The Association among Blood Pressure, Blood Pressure Medications, and Glaucoma in a Nationwide Electronic Health Records Database.Ophthalmology · 2022Article
- Literature Review on Artificial Intelligence Methods for Glaucoma Screening, Segmentation, and Classification.Journal of imaging · 2022Review
- Association of the SNP rs112369934 nearGenes · 2021Article
- The Role of Genetic Ancestry as a Risk Factor for Primary Open-angle Glaucoma in African Americans.Investigative ophthalmology & visual science · 2021Article
- Evaluation of a multimedia marketing campaign to engage African American patients in glaucoma screening.Preventive medicine reports · 2020Article
- Functional brain alterations in auditory hallucination subtypes in individuals with auditory hallucinations without the diagnosis of specific neurological diseases and mental disorders at the current stage.Brain and behavior · 2020Article
- Brain function differences in drug-naïve first-episode auditory verbal hallucination-schizophrenia patients with versus without insight.Chinese medical journal · 2019Article
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Authors and funding
12 authors.
Funding
Abstract
purposeTo determine the relationship between positive family history (FH) and primary open-angle glaucoma (POAG) diagnosis and clinical presentation in the Primary Open-Angle African American Glaucoma Genetics (POAAGG) cohort.
methodsFH of POAG in first-degree relatives was assessed in 2365 subjects in the POAAGG cohort. A standardized interview was used to assess FH of glaucoma, demographic characteristics, lifestyle choices, and medical and ocular comorbidities.
resultsPositive FH was associated with increased risk of POAG (age-adjusted odds ratio and 95% confidence interval 3.4 [2.8, 4.1]). In age-adjusted analysis among POAG cases, positive FH was associated with younger age (P < .001), female sex (P < .001), hypertension (P = .006), use of hypertension medication (P = .03), and prior glaucoma surgery (P = .02). Cases with positive FH also had thicker retinal nerve fiber layers (P = .03).
conclusionsThe risk conferred by positive FH suggests strong genetic underpinnings for some patients with this disease, which will be investigated by genome-wide association studies and whole exome sequencing. NOTE: Publication of this article is sponsored by the American Ophthalmological Society.
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