ArticleThe Journal of pediatrics2018
Neuroinflammation-Related Encephalopathy in an Infant Born Preterm Following Exposure to Maternal Diabetic Ketoacidosis.
David E Mandelbaum, Amanda Arsenault, Barbara S Stonestreet, Stefan Kostadinov, Suzanne M de la Monte
Open access · greenAbstract readCase Reports
In one paragraphArticle in The Journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 3 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
5 authors at 1 institution in 1 country.
David E MandelbaumAlpert Medical School of Brown University, Providence, RI; Department of Neurology, Hasbro Children's Hospital, Providence, RI; Department of Pediatrics, Hasbro Children's Hospital, Providence, RI.
Amanda ArsenaultAlpert Medical School of Brown University, Providence, RI; Department of Pediatrics, Women and Infants Hospital of Rhode Island, Providence, RI.
Barbara S StonestreetAlpert Medical School of Brown University, Providence, RI; Department of Pediatrics, Women and Infants Hospital of Rhode Island, Providence, RI.
Stefan KostadinovAlpert Medical School of Brown University, Providence, RI; Department of Pathology at the Women and Infants Hospital of Rhode Island, Providence, RI.
Suzanne M de la MonteAlpert Medical School of Brown University, Providence, RI; Division of Neuropathology, Rhode Island Hospital, Providence, RI; Department of Pathology, Rhode Island Hospital, Providence, RI; Department of Neurology, Rhode Island Hospital, Providence, RI; Department of Neurosurgery, Rhode Island Hospital, Providence, RI. Electronic address: Suzanne_DeLaMonte_MD@Brown.edu.
Providence College · US
Funding
FASD Inhibition of ASPH-Notch Mediates Adolescent Cerebral White Matter Pathology-Potential Utility of Non-invasive Extracellular Vesicle AssaysR01AA011431 · NIAAA · RHODE ISLAND HOSPITAL (PROVIDENCE, RI) · PI SUZANNE M. DE LA MONTE · 1996 to 2026
$5.4MCytokines and the blood-brain barrier in the ovine fetusR01HD057100 · NICHD · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI STONESTREET, BARBARA S · 2008 to 2020
$3.8MEthanol, IRS-1 Signaling and Neuronal MigrationR37AA011431 · NIAAA · RHODE ISLAND HOSPITAL · PI DE LA MONTE, SUZANNE M. · 2009 to 2018
$3.7MBeneficial Effects of Inter-alpha Inhibitors in Fetal Brain InjuryR21NS096525 · NINDS · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI STONESTREET, BARBARA S · 2016 to 2017
$441kETHANOL, INSULIN/IGF SIGNALING AND NEURONAL MIGRATIONR56AA011431 · NIAAA · RHODE ISLAND HOSPITAL · PI DE LA MONTE, SUZANNE M. · 2008 to 2008
$312kNIAAA NIH HHS R01 AA011431NIAAA NIH HHS R37 AA011431NIAAA NIH HHS R56 AA011431NICHD NIH HHS R01 HD057100NINDS NIH HHS R21 NS096525
6 · The paper itselfAbstract
A pregnant woman with new-onset type 1 diabetes and ketoacidosis delivered an infant at 28 weeks of gestation who died with multiple organ failure and severe cerebral vasculopathy with extensive hemorrhage, diffuse microgliosis, and edema. This illustrates that antenatal metabolic and inflammatory stressors may be associated with neonatal encephalopathy and cerebral hemorrhage.
Indexed as
AdultAutopsyBrain DiseasesDiabetic KetoacidosisFemaleHumansInfant, NewbornInfant, PrematureInfant, Premature, DiseasesMothersMultiple Organ FailurePregnancyPregnancy ComplicationsPrenatal Exposure Delayed Effectshypoxic-ischemic leukoencephalopathyinflammationpregnancyType 1 diabetes
Identifiers
PMID29555093
PMCPMC6091875
OpenAlexW2790223036
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390