Evidence map›Paper›PMID 29555076›Full record

ArticleJournal of biomechanics2018

Impacts of maturation on the micromechanics of the meniscus extracellular matrix.

Qing Li, Chao Wang, Biao Han, Feini Qu, Hao Qi, Christopher Y Li, Robert L Mauck, Lin Han

Abstract read
In one paragraph

Article in Journal of biomechanics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Structure, function, and defect tolerance with maturation of the radial tie fiber network in the knee meniscus.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020
    Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qing LiSchool of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104, United States.
Chao WangSchool of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104, United States.
Biao HanSchool of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104, United States.
Feini QuMcKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States; Translational Musculoskeletal Research Center, Philadelphia Veterans Administration Medical Center, Philadelphia, PA 19104, United States.
Hao QiDepartment of Materials Science and Engineering, Drexel University, Philadelphia, PA 19104, United States.
Christopher Y LiDepartment of Materials Science and Engineering, Drexel University, Philadelphia, PA 19104, United States.
Robert L MauckMcKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States; Translational Musculoskeletal Research Center, Philadelphia Veterans Administration Medical Center, Philadelphia, PA 19104, United States.
Lin HanSchool of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104, United States. Electronic address: lh535@drexel.edu.

Funding

Overall: Resource-based Center for Musculoskeletal Disorders Research (Overall Application)P30AR069619 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI LOUIS J SOSLOWSKY · 2016 to 2026
$9.1M
The Role of Hyaluronic Acid Receptors in Tendon HealingP30AR050950 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI SOSLOWSKY, LOUIS J · 2006 to 2015
$6.2M
Multi-scale biomechanics of engineered and native fibrous load-bearing tissueR01EB002425 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI ELLIOTT, DAWN M, MAUCK, ROBERT L · 2003 to 2017
$4.1M
Biomechanical Engineering of Fibrous Load-Bearing TissueR56EB002425 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI ELLIOTT, DAWN M · 2007 to 2007
$365k
Roles of Decorin and Biglycan in Cartilage Nanomechanics and OsteoarthritisR21AR066824 · NIAMS · DREXEL UNIVERSITY · PI HAN, LIN · 2015 to 2016
$357k
NIAMS NIH HHS P30 AR050950NIAMS NIH HHS P30 AR069619NIAMS NIH HHS R21 AR066824NIBIB NIH HHS R01 EB002425NIBIB NIH HHS R56 EB002425
6 · The paper itself

Abstract

To elucidate how maturation impacts the structure and mechanics of meniscus extracellular matrix (ECM) at the length scale of collagen fibrils and fibers, we tested the micromechanical properties of fetal and adult bovine menisci via atomic force microscopy (AFM)-nanoindentation. For circumferential fibers, we detected significant increase in the effective indentation modulus, E

Indexed as

AnimalsCattleExtracellular MatrixFemaleFetusFibrillar CollagensMeniscusMicroscopy, Atomic ForceFibrillar CollagensCollagen fibersExtracellular matrixMaturationMeniscusNanoindentation

Identifiers

PMID29555076
PMCPMC5895496

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.