ArticleParasites & vectors2018
Ehrlichia spp. infection in rural dogs from remote indigenous villages in north-eastern Brazil.
Article in Parasites & vectors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 53 citations in OpenAlex.
- Canine vector-borne diseases: a changing world demands a new preventive strategy from veterinarians.Parasites & vectors · 2026Review
- A multidimensional analysis of the risk of infection with Ehrlichia canis among urban dogs in Iquitos, Peru.Scientific reports · 2025Article
- Co-infection patterns of vector-borne zoonotic pathogens in owned free-ranging dogs in central Chile.Veterinary research communications · 2023Article
- Filarial nematodes in domestic dogs and mosquitoes (Diptera: Culicidae) from semi-rural areas in Central Chile.Frontiers in veterinary science · 2023Article
- Occurrence of tick-borne pathogens in dogs in a coastal region of the state of Ceará, northeastern Brazil.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2022Article
- Molecular Evidence ofAnimals : an open access journal from MDPI · 2020Article
- Prevalence and incidence of vector-borne pathogens in unprotected dogs in two Brazilian regions.Parasites & vectors · 2020Article
- A review on the occurrence of companion vector-borne diseases in pet animals in Latin America.Parasites & vectors · 2019Review
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundEhrlichia canis is a tick-borne bacterium that causes severe, life-threatening disease in dogs, being more prevalent in tropical and subtropical countries. Randomized studies conducted in Brazil indicate that the prevalence of E. canis infection in dogs ranges from 0.7% to over 50.0%. In a study conducted in northern Brazil, the prevalence was higher in dogs from urban areas, as compared to dogs from rural areas. In the present study, we investigated the exposure to Ehrlichia spp. infection in dogs from remote indigenous villages located in a rural area in north-eastern Brazil.
methodsFrom March to June 2015, 300 privately owned dogs were blood sampled and tested by a rapid ELISA and by a conventional PCR in order to detect anti-Ehrlichia spp. antibodies and E. canis DNA, respectively. Additionally, dogs were also tested for anti-Anaplasma spp. antibodies and Anaplasma platys DNA, using the same diagnostic approaches. Positivity was correlated with tick infestation and dogs' data (gender, age and level of restriction).
resultsOverall, 212 (70.7%) dogs were positive for at least one test targeting Ehrlichia spp. In particular, 173 (57.7%) dogs were positive only by rapid ELISA, 5 (1.7%) only by PCR and 34 (11.4%) were simultaneously positive by both tests. In the same way, 39 (13.0%) dogs presented detectable E. canis DNA in their blood, whereas 18 (6.0%) dogs were A. platys DNA-positive. Coupling serological and PCR data, 63 (21.0%) dogs were simultaneously positive to Ehrlichia spp. and Anaplasma spp. Positivity rates for both Ehrlichia spp. and Anaplasma spp. were higher among dogs more than 1 year of age. Sick dogs were more positive to Ehrlichia spp. as compared to healthy dogs.
conclusionsDogs from rural areas in north-eastern Brazil are highly exposed to Ehrlichia spp. infection and positivity rates do not necessarily correlate with current tick infestation load, since only one infected tick bite is needed to get the infection. This reinforces the importance of keeping dogs free of ticks, in order to reduce as much as possible the risk of infection by E. canis and other tick-borne pathogens such as Babesia vogeli, which are usually co-endemic.
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