ArticleAmerican journal of epidemiology2018
Associations Between Maternal Obesity and Pregnancy Hyperglycemia and Timing of Puberty Onset in Adolescent Girls: A Population-Based Study.
Article in American journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Pubertal timing in boys and girls born to mothers with gestational diabetes mellitus: a systematic review.European journal of endocrinology · 2021Pooled it
- Maternal pre-pregnancy overweight/obesity, in-utero exposure to toxic heavy metals, and offspring age at peak height velocity: A prospective birth cohort study.Environmental research · 2025Article
- The Impact of Gestational Diabetes Mellitus on Minipuberty in Girls.International journal of molecular sciences · 2024Article
- Beyond defence: Immune architects of ovarian health and disease.Seminars in immunopathology · 2024Review
- Maternal and prenatal factors and age at thelarche in the LEGACY Girls Study cohort: implications for breast cancer risk.International journal of epidemiology · 2023Article
- Article
- Early programming of reproductive health and fertility: novel neuroendocrine mechanisms and implications in reproductive medicine.Human reproduction update · 2022Review
- Associations between infant growth and pubertal onset timing in a multiethnic prospective cohort of girls.BMC pediatrics · 2022Article
- Analysis of Early-Life Growth and Age at Pubertal Onset in US Children.JAMA network open · 2022Article
- Childhood Overweight and Obesity and Pubertal Onset Among Mexican-American Boys and Girls in the CHAMACOS Longitudinal Study.American journal of epidemiology · 2022Article
- Association of mode of delivery with offspring pubertal development in Project Viva: a prospective pre-birth cohort study in the USA.Human reproduction (Oxford, England) · 2021Article
- Early-life exposures and age at thelarche in the Sister Study cohort.Breast cancer research : BCR · 2021Article
- BMI status relative to international and national growth references among Pakistani school-age girls.BMC pediatrics · 2021Article
- Pervasive structural racism in environmental epidemiology.Environmental health : a global access science source · 2021Article
- Trajectory of Body Mass Index from Ages 2 to 7 Years and Age at Peak Height Velocity in Boys and Girls.The Journal of pediatrics · 2021Article
- Association between factors related to the pregnancy, neonatal period, and later complications (especially asthma) and menarcheal age in a sample of Lebanese girls.BMC women's health · 2020Article
- Association between indicators of systemic inflammation biomarkers during puberty with breast density and onset of menarche.Breast cancer research : BCR · 2020Article
- Connections Between Obesity and Puberty: Invited by Manuel Tena-Sempere, Cordoba.Current opinion in endocrine and metabolic research · 2020Article
- Parental Obesity and Offspring Pubertal Development: Project Viva.The Journal of pediatrics · 2019Article
- Maternal pre-pregnancy obesity and timing of puberty in sons and daughters: a population-based cohort study.International journal of epidemiology · 2019Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
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Abstract
Early puberty is associated with adverse health outcomes. We investigated whether in utero exposure to maternal obesity is associated with daughters' pubertal timing using 15,267 racially/ethnically diverse Kaiser Permanente Northern California members aged 6-11 years with pediatrician-assessed Tanner staging (2003-2017). We calculated maternal body mass index (BMI; weight (kg)/height (m)2) during pregnancy from the electronic health record data. Using a proportional hazards model with interval censoring, we examined the associations between maternal obesity and girls' pubertal timing, as well as effect modification by race/ethnicity and mediation by prepubertal BMI. Maternal obesity (BMI ≥30) and overweight (BMI 25-29.9) were associated with earlier onset of breast development in girls (hazard ratio (HR) = 1.39 (95% confidence interval (CI): 1.30, 1.49) and HR = 1.21 (95% CI: 1.13, 1.29), respectively), after adjustment for girl's race/ethnicity, maternal age, education, parity, and smoking during pregnancy. There was interaction by race/ethnicity for associations between maternal obesity and girls' pubic hair onset: Associations were strongest among Asian and non-Hispanic white girls (HR = 1.53 (95% CI: 1.24, 1.90) and HR = 1.34 (95% CI: 1.18, 1.52), respectively) and absent for African-American girls. Adjustment for girl's prepubertal BMI only slightly attenuated associations. Our results suggest the importance of maternal metabolic factors during pregnancy in the timing of girls' puberty and potential differences in the associations by race/ethnicity.
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