ArticleCornea2018
A Comparative Study of Central Corneal Epithelial, Stromal, and Total Thickness in Males With and Without Primary Open-Angle Glaucoma.
Article in Cornea, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 21 citations in OpenAlex.
- Polypharmacy in glaucoma management: a narrative review.Irish journal of medical science · 2026Review
- Impact of Antiglaucoma Drug Number and Class on Corneal Epithelial Thickness Measured by OCT.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Ethnic and sex differences in corneal nerves and corneal epithelial cells in healthy population.Frontiers in medicine · 2025Article
- Corneal thickness and endothelial change after use of ocular hypotensive agents.The Kaohsiung journal of medical sciences · 2024Article
- Corneal stromal mapping characteristics in normal corneas using anterior segment SD-OCT.Frontiers in medicine · 2024Article
- Wide Corneal Epithelial Thickness Mapping in Eyes With Topical Antiglaucoma Therapy Using Optical Coherence Tomography.Translational vision science & technology · 2022Article
- Changes in Corneal Epithelial Thickness Induced by Topical Antiglaucoma Medications.Journal of clinical medicine · 2021Article
- Confocal Microscopy and Anterior Segment Optical Coherence Tomography Imaging of the Ocular Surface and Bleb Morphology in Medically and Surgically Treated Glaucoma Patients: A Review.Pharmaceuticals (Basel, Switzerland) · 2021Review
- The frequency of non-pathologically thin corneas in young healthy adults.Clinical ophthalmology (Auckland, N.Z.) · 2019Article
- Comparison of focal loss volume, global loss volume, retinal nerve fiber layer thickness, and corneal epithelial thickness in eyes with glaucoma and suspicious optic discs.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
purposeTo compare the central corneal epithelial thickness (CET), stromal thickness (CST), and total thickness (CCT) in males with and without primary open-angle glaucoma and to determine the factors associated with corneal thickness.
methodsA case-control study was conducted to evaluate 116 male patients at the Miami Veterans Affair Medical Center. Subjects with available anterior segment optical coherence tomography images (Cirrus HD-OCT, Carl Zeiss Meditec Inc, Dublin, CA) were retrospectively classified into 2 groups by glaucoma status. CET, CST, and CCT measurements between the groups were compared. Associations between thickness and other variables of interest were also evaluated.
resultsThe 2 groups were similar with respect to race and ethnicity. Mean age of patients in the glaucoma group (70.3 ± 8.9) was higher than in the nonglaucoma group (66.0 ± 11.7), P < 0.03. Individuals who self-identified as black had lower CST (447.8 ± 29.0 μm) and CCT (503.0 ± 30.5 μm) compared with whites (CST: 470.0 ± 31.7 μm; CCT: 525.1 ± 32.4 μm), P = 0.0001 and P = 0.0002, respectively. In a similar manner, individuals with glaucoma had lower CST (453.4 ± 32.5 μm) and CCT (507.3 ± 33.8 μm) than that of those without glaucoma (CST: 465.2 ± 31.2 μm; CCT: 521.5 ± 31.5 μm), P = 0.05 and P = 0.02, respectively. CET, CST, and CCT were negatively correlated with the number of antiglaucoma medications (r = -0.2, r = -0.22, and r = -0.25, respectively), P = 0.05 for all.
conclusionsIndividuals with glaucoma have lower CST and CCT measurements compared with individuals without glaucoma. An increased number of glaucoma medications were associated with lower thickness measurements.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.