ArticleEmerging infectious diseases2018
Rickettsial Illnesses as Important Causes of Febrile Illness in Chittagong, Bangladesh.
Article in Emerging infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diversity of infectious aetiologies of acute undifferentiated febrile illnesses in south and Southeast Asia: a systematic review.BMC infectious diseases · 2019Pooled it
- The temporal dynamics of humoral immunity to Rickettsia typhi infection in murine typhus patients.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2020Trial
- Rickettsial Diseases and Vaccines: Is There an Opportunity for Plant-Made Vaccine Technology?Biotechnology and bioengineering · 2026Review
- Acute febrile illness in remote and rural communities: Perspectives of health providers and managers in Chattogram, Bangladesh.SSM - health systems · 2025Article
- Epidemiological features of scrub typhus and molecular characteristics ofIJID regions · 2025Article
- Tick-, flea- and mite-borne pathogens and associated diseases of public health importance in Bangladesh: a review.Infectious medicine · 2024Review
- Rickettsial Infections Are Neglected Causes of Acute Febrile Illness in Teluk Intan, Peninsular Malaysia.Tropical medicine and infectious disease · 2022Article
- Simple clinical and laboratory predictors to improve empirical treatment strategies in areas of high scrub typhus and dengue endemicity, central Vietnam.PLoS neglected tropical diseases · 2022Article
- Outbreak prone communicable diseases of public health importance in the northern districts of West Bengal - Current status & the way forward.The Indian journal of medical research · 2021Review
- Molecular characterization ofNew microbes and new infections · 2019Article
- Seroprevalence of typhus group rickettsial infections in the north-east region of India.The Indian journal of medical research · 2019Article
- Epidemiology, Risk Factors and Seasonal Variation of Scrub Typhus Fever in Central Nepal.Tropical medicine and infectious disease · 2019Article
- Diagnosis of Murine Typhus by Serology in Peninsular Malaysia: A Case Report Where Rickettsial Illnesses, Leptospirosis and Dengue Co-Circulate.Tropical medicine and infectious disease · 2019Article
- Diagnostic Accuracy of the InBios Scrub Typhus Detect™ ELISA for the Detection of IgM Antibodies in Chittagong, Bangladesh.Tropical medicine and infectious disease · 2018Article
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Authors and funding
24 authors.
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Abstract
We conducted a yearlong prospective study of febrile patients admitted to a tertiary referral hospital in Chittagong, Bangladesh, to assess the proportion of patients with rickettsial illnesses and identify the causative pathogens, strain genotypes, and associated seasonality patterns. We diagnosed scrub typhus in 16.8% (70/416) and murine typhus in 5.8% (24/416) of patients; 2 patients had infections attributable to undifferentiated Rickettsia spp. and 2 had DNA sequence-confirmed R. felis infection. Orientia tsutsugamushi genotypes included Karp, Gilliam, Kato, and TA763-like strains, with a prominence of Karp-like strains. Scrub typhus admissions peaked in a biphasic pattern before and after the rainy season, whereas murine typhus more frequently occurred before the rainy season. Death occurred in 4% (18/416) of cases; case-fatality rates were 4% each for scrub typhus (3/70) and murine typhus (1/28). Overall, 23.1% (96/416) of patients had evidence of treatable rickettsial illnesses, providing important evidence toward optimizing empirical treatment strategies.
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