ReviewJournal of toxicology and environmental health. Part B, Critical reviews2018
In vivo and in vitro methods for evaluating soil arsenic bioavailability: relevant to human health risk assessment.
Review in Journal of toxicology and environmental health. Part B, Critical reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Interconnected soil iron and arsenic speciation effects on arsenic bioaccessibility and bioavailability: a scoping review.Journal of toxicology and environmental health. Part B, Critical reviews · 2022Pooled it
- Human health risk and remedial goal assessment using Monte Carlo simulation: a case study of arsenic contaminated allotment gardens in southern Poland.Environmental geochemistry and health · 2026Article
- Contrasting Effects of Phosphate on Arsenic Mobility and Human Exposure in Agricultural Soils.GeoHealth · 2026Article
- Sub-20 nm Hard X-ray Spectromicroscopy Reveals Nanoscale Redox Heterogeneity in Ultrafine Particulates.ACS nano · 2026Article
- Evaluating the pollution footprint of traffic-derived trace elements in roadside soil and the associated risks in a non-metropolitan city.Environmental monitoring and assessment · 2026Article
- High-Dietary Fiber Diet Reduces Arsenic Oral Bioavailability and Health Risk from Soils by Regulating Gut Microbiota and Intestinal Barrier Function.Foods (Basel, Switzerland) · 2026Article
- Dynamic Telomere Length Response to Neurodevelopmental Arsenic Exposure: Insights into Transcriptional Regulation and Neuronal Morphogenesis.Environment & health (Washington, D.C.) · 2025Article
- Analysis of changes and influencing factors of stablization treatment effects and bioavailability after freeze-thaw: a case study of Pb-contaminated soil in a non-ferrous metal factory in Northeast China.Frontiers in microbiology · 2024Article
- Dermal and oral exposure risks to heavy metals from 3D printing metal-fill thermoplastics.The Science of the total environment · 2023Article
- Article
- Molecular speciation controls arsenic and lead bioaccessibility in fugitive dusts from sulfidic mine tailings.Environmental science. Processes & impacts · 2023Article
- Evaluating the mouse model for estimation of arsenic bioavailability: Comparison of estimates of absolute bioavailability of inorganic arsenic in mouse, humans, and other species.Journal of toxicology and environmental health. Part A · 2022Article
- Bioaccessibility of arsenic from contaminated soils and alteration of the gut microbiome in an in vitro gastrointestinal model.Environmental pollution (Barking, Essex : 1987) · 2022Article
- Bioaccessible arsenic in soil of thermal areas of Viterbo, Central Italy: implications for human health risk.Environmental geochemistry and health · 2022Article
- Improving the predictive value of bioaccessibility assays and their use to provide mechanistic insights into bioavailability for toxic metals/metalloids - A research prospectus.Journal of toxicology and environmental health. Part B, Critical reviews · 2021Review
- Development of a whole-cell biosensor based on an ArsR-PEnvironmental science and ecotechnology · 2021Article
- Binding and Activity of Tetrabromobisphenol A Mono-Ether Structural Analogs to Thyroid Hormone Transport Proteins and Receptors.Environmental health perspectives · 2020Article
- Arsenic Accumulation of Realgar Altered by Disruption of Gut Microbiota in Mice.Evidence-based complementary and alternative medicine : eCAM · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
Arsenic (As) is the most frequently occurring contaminant on the priority list of hazardous substances, which lists substances of greatest public health concern to people living at or near U.S. National Priorities List site. Accurate assessment of human health risks from exposure to As-contaminated soils depends on estimating its bioavailability, defined as the fraction of ingested As absorbed across the gastrointestinal barrier and available for systemic distribution and metabolism. Arsenic bioavailability varies among soils and is influenced by site-specific soil physical and chemical characteristics and internal biological factors. This review describes the state-of-the science that supports our understanding of oral bioavailability of soil As, the methods that are currently being explored for estimating soil As relative bioavailability (RBA), and future research areas that could improve our prediction of the oral RBA of soil As in humans. The following topics are addressed: (1) As soil geochemistry; (2) As toxicology; (3) in vivo models for estimating As RBA; (4) in vitro bioaccessibility methods; and (5) conclusions and research needs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.