Evidence map›Paper›PMID 29553832›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2018

Deficient transient receptor potential vanilloid type 4 function contributes to compromised [Ca

Viktor Tomilin, Gail A Reif, Oleg Zaika, Darren P Wallace, Oleh Pochynyuk

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Glycosylation in kidney diseases.Precision clinical medicine · 2025
    Review
  2. Review
  3. TRPV4 expression in the renal tubule is necessary for maintaining whole body KAmerican journal of physiology. Renal physiology · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. TRPV4: A Physio and Pathophysiologically Significant Ion Channel.International journal of molecular sciences · 2020
    Review
  12. Review
  13. Article
  14. TRPV4 deletion protects against hypokalemia during systemic KAmerican journal of physiology. Renal physiology · 2019
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Viktor TomilinDepartment of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA; and.
Gail A ReifThe Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, Kansas, USA.
Oleg ZaikaDepartment of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA; and.
Darren P WallaceThe Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, Kansas, USA.
Oleh PochynyukDepartment of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA; and.
The University of Texas Health Science Center at Houston · USUniversity of Kansas Medical Center · US

Funding

Transgenic & Gene-Targeting Shared ResourceP30CA168524 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI ROY A. JENSEN · 2012 to 2026
$40.1M
Pilot and Feasibility CoreP30DK106912 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI CALVET, JAMES P · 2015 to 2019
$5.5M
Role of Periostin in Polycystic Kidney DiseaseR01DK081579 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI WALLACE, DARREN P. · 2009 to 2018
$3.0M
Aldosterone-independent regulation of ENaC by systemic saltR01DK095029 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI POCHYNYUK, OLEH · 2012 to 2016
$1.6M
NCI NIH HHS P30 CA168524NIDDK NIH HHS P30 DK106912NIDDK NIH HHS R01 DK081579NIDDK NIH HHS R01 DK095029
6 · The paper itself

Abstract

Autosomal-dominant polycystic kidney disease (ADPKD) is a devastating disorder that is characterized by a progressive decline in renal function as a result of the development of fluid-filled cysts. Defective flow-mediated [Ca

Indexed as

AnimalsCalciumCells, CulturedCHO CellsCricetulusGlycosylationHomeostasisHumansKidneyMiddle AgedPolycystic Kidney, Autosomal DominantSignal TransductionTRPV Cation ChannelsCalciumTRPV4 protein, humanTRPV Cation Channelsdistal tubuleglycosylationpolycystins

Identifiers

PMID29553832
PMCPMC6044056
OpenAlexW2791934036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.