Evidence map›Paper›PMID 29553563›Full record

ArticleJournal of visualized experiments : JoVE2018

Preparation, Purification, and Use of Fatty Acid-containing Liposomes.

Lin Jin, Aaron E Engelhart, Katarzyna P Adamala, Jack W Szostak

Open access · bronzeAbstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Sequential gentle hydration increases encapsulation in model protocells.bioRxiv : the preprint server for biology · 2023
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Lipid Vesicle-Coated Complex Coacervates.Langmuir : the ACS journal of surfaces and colloids · 2019
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Lin JinHoward Hughes Medical Institute and Department of Molecular Biology and Center for Computational and Integrative Biology, Massachusetts General Hospital; Department of Biomedical Engineering, Boston University.
Aaron E EngelhartHoward Hughes Medical Institute and Department of Molecular Biology and Center for Computational and Integrative Biology, Massachusetts General Hospital; Department of Genetics, Cell Biology, and Development, University of Minnesota.
Katarzyna P AdamalaHoward Hughes Medical Institute and Department of Molecular Biology and Center for Computational and Integrative Biology, Massachusetts General Hospital; Department of Genetics, Cell Biology, and Development, University of Minnesota.
Jack W SzostakHoward Hughes Medical Institute and Department of Molecular Biology and Center for Computational and Integrative Biology, Massachusetts General Hospital; szostak@molbio.mgh.harvard.edu.
Howard Hughes Medical Institute · USUniversity of Minnesota · US

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

Liposomes containing single-chain amphiphiles, particularly fatty acids, exhibit distinct properties compared to those containing diacylphospholipids due to the unique chemical properties of these amphiphiles. In particular, fatty acid liposomes enhance dynamic character, due to the relatively high solubility of single-chain amphiphiles. Similarly, liposomes containing free fatty acids are more sensitive to salt and divalent cations, due to the strong interactions between the carboxylic acid head groups and metal ions. Here we illustrate techniques for preparation, purification, and use of liposomes comprised in part or whole of single chain amphiphiles (e.g., oleic acids).

Indexed as

Fatty AcidsLiposomesFatty AcidsLiposomes

Identifiers

PMID29553563
PMCPMC5912384
OpenAlexW2786576354

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.