Evidence map›Paper›PMID 29553490›Full record

ArticleJournal of visualized experiments : JoVE2018

Electrophysiological Assessment of Murine Atria with High-Resolution Optical Mapping.

Kensuke Ihara, Koji Sugiyama, Kentaro Takahashi, Masahiro Yamazoe, Tetsuo Sasano, Tetsushi Furukawa

Abstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kensuke IharaDepartment of Bio-informational Pharmacology, Medical Research Institute, Tokyo Medical and Dental University.
Koji SugiyamaDepartment of Bio-informational Pharmacology, Medical Research Institute, Tokyo Medical and Dental University.
Kentaro TakahashiDepartment of Bio-informational Pharmacology, Medical Research Institute, Tokyo Medical and Dental University.
Masahiro YamazoeDepartment of Bio-informational Pharmacology, Medical Research Institute, Tokyo Medical and Dental University.
Tetsuo SasanoDepartment of Biofunctional Informatics, Tokyo Medical and Dental University; sasano.bi@tmd.ac.jp.
Tetsushi FurukawaDepartment of Bio-informational Pharmacology, Medical Research Institute, Tokyo Medical and Dental University.
Tokyo Medical and Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent genome-wide association studies targeting atrial fibrillation (AF) have indicated a strong association between the genotype and electrophysiological phenotype in the atria. That encourages us to utilize a genetically-engineered mouse model to elucidate the mechanism of AF. However, it is difficult to evaluate the electrophysiological properties in murine atria due to their small size. This protocol describes the electrophysiological evaluation of atria using an optical mapping system with a high temporal and spatial resolution in Langendorff perfused murine hearts. The optical mapping system is assembled with dual high-speed complementary metal oxide semiconductor cameras and high magnification objective lenses, to detect the fluorescence of a voltage-sensitive dye and Ca

Indexed as

AnimalsCardiac ElectrophysiologyHeart AtriaHeart Conduction SystemMice

Identifiers

PMID29553490
PMCPMC5931326
OpenAlexW2789014032

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.