ArticleEnvironmental health perspectives2018
Air Toxics in Relation to Autism Diagnosis, Phenotype, and Severity in a U.S. Family-Based Study.
Article in Environmental health perspectives, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Evidence of susceptibility to autism risks associated with early life ambient air pollution: A systematic review.Environmental research · 2022Pooled it
- Environmental metal exposure and autism spectrum disorder: spatial analysis of exposure patterns and associated risk among children in Alabama.Environmental science and pollution research international · 2026Article
- Essential and non-essential metals in children's intellectual functioning: A multi-media biomarker approach from a Mexico City birth cohort.Environmental research · 2025Article
- Evaluating the efficacy of the VAMS Mitra microsampler for whole blood trace element analysis.Bioanalysis · 2025Article
- The effects of parental occupational exposures on autism spectrum disorder severity and skills in cognitive and adaptive domains in children with autism spectrum disorder.International journal of hygiene and environmental health · 2025Article
- Inequality in Hazardous Air Pollutant Emissions and Concentrations Measured Over Los Angeles.Environmental science & technology · 2025Article
- Expanding Research on Contextual Factors in Autism Research: What Took Us So Long?Autism research : official journal of the International Society for Autism Research · 2025Article
- Ambient Toxic Air Contaminants in the Maternal Residential Area during Pregnancy and Cerebral Palsy in the Offspring.Environmental health perspectives · 2025Article
- Maternal residential exposure to solvents from industrial sources during pregnancy and childhood cancer risk in California.International journal of hygiene and environmental health · 2024Article
- Ultrafine particulate matter exposure during second year of life, but not before, associated with increased risk of autism spectrum disorder in BKMR mixtures model of multiple air pollutants.Environmental research · 2024Article
- Prenatal socioenvironmental exposures and autism spectrum disorder: A web of confusion.Child development perspectives · 2023Article
- The association between dietary fiber intake and the concentrations of aldehydes in serum.Environmental science and pollution research international · 2022Article
- Environmental exposures associated with elevated risk for autism spectrum disorder may augment the burden of deleterious de novo mutations among probands.Molecular psychiatry · 2022Review
- What is autism?Pharmacological reports : PR · 2021Review
- In utero immune programming of autism spectrum disorder (ASD).Human immunology · 2021Article
- Benefits, Burden, and COVID-19: A Response to Dutheil et al. (2020).Journal of autism and developmental disorders · 2021Article
- Maternal immune response and air pollution exposure during pregnancy: insights from the Early Markers for Autism (EMA) study.Journal of neurodevelopmental disorders · 2020Article
- The status of chemical elements in the blood plasma of children with autism spectrum disorder in Tunisia: a case-control study.Environmental science and pollution research international · 2020Article
- Phthalates and Autistic Traits: Exploring the Association between Prenatal Exposures and Child Behavior.Environmental health perspectives · 2020Article
- Developmental exposure to near roadway pollution produces behavioral phenotypes relevant to neurodevelopmental disorders in juvenile rats.Translational psychiatry · 2020Article
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Authors and funding
9 authors at 7 institutions in 1 country.
Funding
Abstract
backgroundPrevious studies have reported associations of perinatal exposure to air toxics, including some metals and volatile organic compounds, with autism spectrum disorder (ASD).
objectivesOur goal was to further explore associations of perinatal air toxics with ASD and associated quantitative traits in high-risk multiplex families.
methodsWe included participants of a U.S. family-based study [the Autism Genetic Resource Exchange (AGRE)] who were born between 1994 and 2007 and had address information. We assessed associations between average annual concentrations at birth for each of 155 air toxics from the U.S. EPA emissions-based National-scale Air Toxics Assessment and
resultsASD diagnosis was positively associated with propionaldehyde, methyl
conclusionsSome air toxics were associated with ASD risk and severity, including some traffic-related air pollutants and newly-reported associations, but other previously reported associations with metals and volatile organic compounds were not reproducible. https://doi.org/10.1289/EHP1867.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.