ArticleeLife2018
Synapse maintenance and restoration in the retina by NGL2.
Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- Utilizing a culture system for horizontal cells to study neural circuit assembly in the developing mouse retina.Frontiers in cellular neuroscience · 2026Article
- Cellular and Molecular Mechanisms Regulating Retinal Synapse Development.Annual review of vision science · 2024Review
- Cell numbers, cell ratios, and developmental plasticity in the rod pathway of the mouse retina.Journal of anatomy · 2023Review
- AMIGO1 Promotes Axon Growth and Territory Matching in the Retina.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Establishment and Maintenance of Neural Circuit Architecture.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Review
- Helical Fasciculation of Bipolar and Horizontal Cell Neurites for Wiring With Photoreceptors in Macaque and Mouse Retinas.Investigative ophthalmology & visual science · 2021Article
- Molecular mechanisms regulating synaptic specificity and retinal circuit formation.Wiley interdisciplinary reviews. Developmental biology · 2021Review
- Brainwide Genetic Sparse Cell Labeling to Illuminate the Morphology of Neurons and Glia with Cre-Dependent MORF Mice.Neuron · 2020Article
- Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide.Oncogene · 2020Article
- Neural Mechanisms Underlying Repetitive Behaviors in Rodent Models of Autism Spectrum Disorders.Frontiers in cellular neuroscience · 2020Review
- AMIGO2 Scales Dendrite Arbors in the Retina.Cell reports · 2019Article
- Presynaptic Expression of LRIT3 Transsynaptically Organizes the Postsynaptic Glutamate Signaling Complex Containing TRPM1.Cell reports · 2019Article
- Rod Bipolar Cells Require Horizontal Cells for Invagination Into the Terminals of Rod Photoreceptors.Frontiers in cellular neuroscience · 2019Article
- Dendrite morphogenesis from birth to adulthood.Current opinion in neurobiology · 2018Review
- Axon Terminal Arbors of Retinal Horizontal Cells Lose Control.Frontiers in neural circuits · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Synaptic cell adhesion molecules (CAMs) promote synapse formation in the developing nervous system. To what extent they maintain and can restore connections in the mature nervous system is unknown. Furthermore, how synaptic CAMs affect the growth of synapse-bearing neurites is unclear. Here, we use adeno-associated viruses (AAVs) to delete, re-, and overexpress the synaptic CAM NGL2 in individual retinal horizontal cells. When we removed NGL2 from horizontal cells, their axons overgrew and formed fewer synapses, irrespective of whether
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.