Evidence map›Paper›PMID 29553308›Full record

ArticleGlobal health action2018

Operational research within a Global Fund supported tuberculosis project in India: why, how and its contribution towards change in policy and practice.

Karuna D Sagili, Srinath Satyanarayana, Sarabjit S Chadha, Nevin C Wilson, Ajay M V Kumar, Patrick K Moonan, John E Oeltmann, Vineet K Chadha, Sharath Burugina Nagaraja, Smita Ghosh and 14 more

Open access · goldAbstract read
In one paragraph

Article in Global health action, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 9 institutions in 5 countries.

Karuna D Sagilia Department of Tuberculosis and Communicable Diseases , International Union Against Tuberculosis and Lung Disease, South-East Asia Regional Office , New Delhi , India.
Srinath Satyanarayanab Centre for Operational Research , International Union Against Tuberculosis and Lung Disease , Paris , France.
Sarabjit S Chadhaa Department of Tuberculosis and Communicable Diseases , International Union Against Tuberculosis and Lung Disease, South-East Asia Regional Office , New Delhi , India.
Nevin C Wilsonc Independent Senior Public Health Consultant , Nilgiris , Tamil Nadu , India.
Ajay M V Kumarb Centre for Operational Research , International Union Against Tuberculosis and Lung Disease , Paris , France.
Patrick K Moonand Division of Global HIV and Tuberculosis , US Centers for Disease Control , Atlanta , GA , USA.ORCID 0000-0002-3550-2065
John E Oeltmannd Division of Global HIV and Tuberculosis , US Centers for Disease Control , Atlanta , GA , USA.
Vineet K Chadhae Epidemiology and Research Division , National Tuberculosis Institute , Bangalore , India.
Sharath Burugina Nagarajaf Department of Community Medicine , ESIC Medical college and PGIMSR , Bangalore , India.
Smita Ghoshd Division of Global HIV and Tuberculosis , US Centers for Disease Control , Atlanta , GA , USA.
Terrence Q Lod Division of Global HIV and Tuberculosis , US Centers for Disease Control , Atlanta , GA , USA.
Tyson Volkmannd Division of Global HIV and Tuberculosis , US Centers for Disease Control , Atlanta , GA , USA.
Matthew Willisd Division of Global HIV and Tuberculosis , US Centers for Disease Control , Atlanta , GA , USA.
Kalpita Shringarpureg Department of Community Medicine , Government Medical College and SSG Hospital , Vadodara , India.
Ravichandra Chinnappa Reddyh National Tuberculosis Institute , Bangalore , India.
Prahlad Kumarh National Tuberculosis Institute , Bangalore , India.
Sreenivas A Nairi World Health Organisation India Country Office , New Delhi , India.
Raghuram Raoj Central Tuberculosis Division , Ministry of Health and Family Welfare, Government of India.
Mohammed Yassink The Global Fund to fight AIDS , Tuberculosis and Malaria , Geneva , Switzerland.
Perry Mwangalak The Global Fund to fight AIDS , Tuberculosis and Malaria , Geneva , Switzerland.
Rony Zachariahl Médecins sans Frontières , Brussels Operational Center (LuxoR) , Luxembourg City , Luxembourg.
Jamhoih Tonsingm International Union Against Tuberculosis and Lung Disease , South-East Asia Regional Office , New Delhi , India.
Anthony D Harriesb Centre for Operational Research , International Union Against Tuberculosis and Lung Disease , Paris , France.
Sunil Khapardej Central Tuberculosis Division , Ministry of Health and Family Welfare, Government of India.
Centers for Disease Control and Prevention · USInternational Union Against Tuberculosis and Lung Disease · FRNational Tuberculosis Institute · INGlobal Fund to Fight AIDS, Tuberculosis and Malaria · CHGovernment of India · INGovernment Medical College · INMédecins Sans Frontières · LUPandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences · INWorld Health Organization - India · IN

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundThe Global Fund encourages operational research (OR) in all its grants; however very few reports describe this aspect. In India, Project Axshya was supported by a Global Fund grant to improve the reach and visibility of the government Tuberculosis (TB) services among marginalised and vulnerable communities. OR was incorporated to build research capacity of professionals working with the national TB programme and to generate evidence to inform policies and practices.

objectivesTo describe how Project Axshya facilitated building OR capacity within the country, helped in addressing several TB control priority research questions, documented project activities and their outcomes, and influenced policy and practice.

methodsFrom September 2010 to September 2016, three key OR-related activities were implemented. First, practical output-oriented modular training courses were conducted (n = 3) to build research capacity of personnel involved in the TB programme, co-facilitated by The Union, in collaboration with the national TB programme, WHO country office and CDC, Atlanta. Second, two large-scale Knowledge, Attitude and Practice (KAP) surveys were conducted at baseline and mid-project to assess the changes pertaining to TB knowledge, attitudes and practices among the general population, TB patients and health care providers over the project period. Third, studies were conducted to describe the project's core activities and outcomes.

resultsIn the training courses, 44 participant teams were supported to develop research protocols on topics of national priority, resulting in 28 peer-reviewed scientific publications. The KAP surveys and description of project activities resulted in 14 peer-reviewed publications. Of the published papers at least 12 have influenced change in policy or practice.

conclusionsOR within a Global Fund supported TB project has resulted in building OR capacity, facilitating research in areas of national priority and influencing policy and practice. We believe this experience will provide guidance for undertaking OR in Global Fund projects.

Indexed as

Capacity BuildingAntitubercular AgentsBiomedical ResearchHealth PolicyHumansIndiaOperations ResearchResearch DesignTuberculosisAntitubercular AgentsGlobal Fund projectimplementation researchIndiaoperational research (OR)Tuberculosis (TB)

Identifiers

PMID29553308
PMCPMC5912428
OpenAlexW2792518958

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.