Evidence map›Paper›PMID 29552952›Full record

ArticleThe Journal of international medical research2018

Analysis of haemostasis biomarkers in patients with advanced stage lung cancer during hypofractionated radiotherapy treatment.

Edyta Wolny-Rokicka, Katarzyna Brzeźniakiewicz-Janus, Jerzy Wydmański, Andrzej Tukiendorf, Agnieszka Zembroń-Łacny

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of international medical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Analysis of Serum Markers with Regard to Treatment Procedures in Advanced Stage Prostate Cancer Patients.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Article
  3. Article
  4. The Correlation of Blood Parameters with Size in Cases of Neoplastic TumorAsian Pacific journal of cancer prevention : APJCP · 2019
    Article
  5. Observational
  6. Appraisal of Basic-Hemostatic Markers in Lung Cancer Patients During Follow-Up Care After Radiotherapy Treatment.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Article
  7. The Diagnostic Efficacy of Age-Adjusted D-Dimer Cutoff Value and Pretest Probability Scores for Deep Venous Thrombosis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Edyta Wolny-Rokicka1 Department of Radiotherapy, Provincial Multidisciplinary Hospital, Gorzow Wielkopolski, Poland.
Katarzyna Brzeźniakiewicz-Janus2 Faculty of Medicine and Health Sciences, University of Zielona Gora, Zielona Gora, Poland.
Jerzy Wydmański4 Department of Radiotherapy, Centre of Oncology, Maria Sklodowska-Curie Memorial Institute, Gliwice, Poland.
Andrzej Tukiendorf5 Department of Biostatistics, Centre of Oncology, Maria Sklodowska-Curie Memorial Institute, Gliwice, Poland.
Agnieszka Zembroń-Łacny2 Faculty of Medicine and Health Sciences, University of Zielona Gora, Zielona Gora, Poland.
University of Zielona Góra · PLThe Maria Sklodowska-Curie National Research Institute of Oncology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective To investigate the relationship between changes in inflammatory and coagulatory biomarkers before and after short palliative radiotherapy in patients with advanced stage lung cancer. Methods This prospective observational single-centre study enrolled patients with histologically- or cytologically-confirmed lung cancer who were eligible for palliative radiotherapy. Inflammatory and coagulatory biomarkers including complete blood count, D-dimer and fibrinogen levels were evaluated before and after short hypofractionated radiotherapy. Results Seventy-two patients with advanced stage lung carcinoma were enrolled in this study. Metastases were associated with an increase in white blood cells, neutrophils and mean platelet volume. Increased volume of the primary tumour had a borderline level of correlation with white blood cell and neutrophil counts. After radiotherapy, white blood cells, neutrophils, haemoglobin and lymphocyte counts were decreased. After radiotherapy, the change in fibrinogen and mean platelet volume were borderline significant. Conclusion The levels of inflammatory and coagulatory biomarkers can be used to monitor treatment.

Indexed as

HemostasisRadiation Dose HypofractionationAdultAgedAged, 80 and overBiomarkers, TumorBlood Cell CountCohort StudiesDemographyFemaleFibrin Fibrinogen Degradation ProductsHumansLung NeoplasmsMaleMiddle AgedNeoplasm StagingBiomarkers, TumorFibrin Fibrinogen Degradation Productsfibrin fragment DD-dimerfibrinogeninflammationLung cancerradiotherapy

Identifiers

PMID29552952
PMCPMC5991232
OpenAlexW2791689711

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.