Evidence map›Paper›PMID 29552742›Full record

ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2018

Absence of chronic hepatitis E virus infection in liver transplant recipients: Report from a hyperendemic region.

Pragya Agarwala, Ekta Gupta, Manish Chandra Choudhary, Viniyendra Pamecha

Abstract read
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In one paragraph

Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Observational
  2. Review
  3. Review
  4. Reply to the query "Chronic hepatitis E virus infection by genotype 1".Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2018
    Article
  5. Chronic hepatitis E virus infection by genotype 1-Don't stop looking yet!Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2018
    Article
  6. Prevalence of hepatitis E virus viremia and antibodies among healthy blood donors in India.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2018
    Article
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Pragya AgarwalaDepartment of Clinical Virology, Institute of Liver and Biliary Sciences, D-1, Vasant Kunj, New Delhi, 110 070, India.
Ekta GuptaDepartment of Clinical Virology, Institute of Liver and Biliary Sciences, D-1, Vasant Kunj, New Delhi, 110 070, India. ektagaurisha@gmail.com.
Manish Chandra ChoudharyDepartment of Clinical Virology, Institute of Liver and Biliary Sciences, D-1, Vasant Kunj, New Delhi, 110 070, India.
Viniyendra PamechaDepartment of HPB Surgery, Institute of Liver and Biliary Sciences, D-1, Vasant Kunj, New Delhi, 110 070, India.
Institute of Liver and Biliary Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most cases of chronic hepatitis E virus (HEV) infection in solid organ transplant recipients are attributable to genotype 3. Although India is hyperendemic for HEV genotype 1, chronic infection in transplant patients has not been reported. In this study, 30 liver transplant recipients were followed up by systematic testing for various markers of HEV (IgM, IgG, HEV-Ag, and RNA) on blood and stool samples obtained pre-transplant, and then at 3 and 6 months post-transplant to look for HEV exposure and persistence. Evidence of HEV infection was found in 6 (20%) cases post-transplant but none of the recipients demonstrated active viremia or antigenemia. This suggests that the circulating genotype of HEV in our population might have limited potential to cause chronic infections.

Indexed as

Endemic DiseasesLiver TransplantationAdultChronic DiseaseFemaleFollow-Up StudiesHepatitis EHepatitis E virusHumansIndiaMaleTransplant RecipientsChronic hepatitisLiver diseaseViral hepatitis

Identifiers

PMID29552742
OpenAlexW2790655144

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.