ArticleAmerican journal of ophthalmology case reports2018
Endophthalmitis caused by gram-positive bacteria resistant to vancomycin: Clinical settings, causative organisms, antimicrobial susceptibilities, and treatment outcomes.
Article in American journal of ophthalmology case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 27 citations in OpenAlex.
- Pathogen Spectrum and Antimicrobial Susceptibility Profiles in Culture-Proven Endophthalmitis at a Tertiary Referral Center in China: A Three-Decade Retrospective Study.Antibiotics (Basel, Switzerland) · 2026Article
- The association between treatment method, microbiological findings, and visual acuity in endophthalmitis patients: A retrospective, multi-centred study.Eye (London, England) · 2026Article
- Myeloid Cell-Specific Deletion of AMPKα1 Worsens Ocular Bacterial Infection by Skewing Macrophage Phenotypes.Journal of immunology (Baltimore, Md. : 1950) · 2024Article
- Antibiotic susceptibility in Endophthalmitis Management Study and intravitreal antibiotic practice trend in India-EMS Report #5.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- New Approaches to Overcoming Antimicrobial Resistance in Endophthalmitis.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Intravitreal triple therapy with vancomycin, ceftazidime, and moxifloxacin for bacterial endophthalmitis: A Twelve-year experience.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Role of Antimicrobial Resistance in Outcomes of Acute Endophthalmitis.Antibiotics (Basel, Switzerland) · 2023Article
- Butyrate Ameliorates Intraocular Bacterial Infection by Promoting Autophagy and Attenuating the Inflammatory Response.Infection and immunity · 2023Article
- Emerging Antibiotic Resistance Patterns Affect Visual Outcome Treating Acute Endophthalmitis.Antibiotics (Basel, Switzerland) · 2022Article
- Real-life comparison of three intravitreal antibiotic drug regimens in endophthalmitis.Indian journal of ophthalmology · 2022Article
- Effectiveness of 0.66% Povidone-Iodine Eye Drops on Ocular Surface Flora before Cataract Surgery: A Nationwide Microbiological Study.Journal of clinical medicine · 2021Article
- Integrative metabolomics and transcriptomics identifies itaconate as an adjunct therapy to treat ocular bacterial infection.Cell reports. Medicine · 2021Article
- Urgent Vitrectomy with Vancomycin Infusion, Silicone Oil Endotamponade, and General Antibiotic Treatment in Multiple Cases of Endophthalmitis from a Single Day of Intravitreal Injections-Case Series.Journal of clinical medicine · 2021Article
- Intensive care unit time and prolonged enucleation to processing interval are associated with donor cornea contamination.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020Article
- Preparation andIranian journal of basic medical sciences · 2020Article
- Diversity, compositional and functional differences between gut microbiota of children and adults.Scientific reports · 2020Article
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- A Review of Antimicrobial Therapy for Infectious Uveitis of the Posterior Segment.Medical hypothesis, discovery & innovation ophthalmology journal · 2018Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo report the clinical settings, causative organisms, antimicrobial susceptibilities, and treatment outcomes of patients with endophthalmitis caused by gram-positive bacteria resistant to vancomycin.
methodsRetrospective case series of all patients with culture-proven endophthalmitis caused by gram-positive bacteria resistant to vancomycin between January 2010 and December 2016 in LV Prasad Eye Institute, Visakhapatnam, India.
resultsThe current study included 14 patients. The clinical settings were post-cataract surgery in 8/14 (57.1%) and open globe injury in 6/14 (42.8%). Primary intervention for all patients included tap and intravitreal antibiotic injection. During subsequent follow-up, pars plana vitrectomy was performed in 6 patients and one patient underwent penetrating keratoplasty. Mean number of intravitreal antibiotic injections performed were 3.4 per patient. The most common organisms isolated were coagulase-negative CONCLUSION AND IMPORTANCE: Antimicrobial susceptibility testing may help in selection of suitable antimicrobial agents for repeat intravitreal injection. Inspite of retreatment with intravitreal antibiotics, these patients generally had poor VA outcomes.
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