Evidence map›Paper›PMID 29552403›Full record

ArticleBiomedical optics express2018

Optical property uncertainty estimates for spatial frequency domain imaging.

Vivian Pera, Kavon Karrobi, Syeda Tabassum, Fei Teng, Darren Roblyer

Abstract read
In one paragraph

Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  19. Microvascular imaging of the skin.Physics in medicine and biology · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vivian PeraDepartment of Biomedical Engineering, Boston University, 44 Cummington Mall, Boston, MA 02215, USA.
Kavon KarrobiDepartment of Biomedical Engineering, Boston University, 44 Cummington Mall, Boston, MA 02215, USA.
Syeda TabassumDepartment of Electrical and Computer Engineering, Boston University, 8 Saint Mary's Street, Boston, MA 02215, USA.
Fei TengDepartment of Electrical and Computer Engineering, Boston University, 8 Saint Mary's Street, Boston, MA 02215, USA.
Darren RoblyerDepartment of Biomedical Engineering, Boston University, 44 Cummington Mall, Boston, MA 02215, USA.

Funding

Overcoming Tumor Resistance to Chemotherapy with Multiscale Diffuse and Nonlinear ImagingF99CA223014 · NCI · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI KARROBI, KAVON · 2017 to 2018
$74k
NCI NIH HHS F99 CA223014
6 · The paper itself

Abstract

Spatial frequency domain imaging (SFDI) is a wide-field diffuse optical imaging modality that has attracted considerable interest in recent years. Typically, diffuse reflectance measurements of spatially modulated light are used to quantify the optical absorption and reduced scattering coefficients of tissue, and with these, chromophore concentrations are extracted. However, uncertainties in estimated absorption and reduced scattering coefficients are rarely reported, and we know of no method capable of providing these when look-up table (LUT) algorithms are used to recover the optical properties. We present a method to generate optical property uncertainty estimates from knowledge of diffuse reflectance measurement errors. By employing the Cramér-Rao bound, we can quickly and efficiently explore theoretical SFDI performance as a function of spatial frequencies and sample optical properties, allowing us to optimize spatial frequency selection for a given application. In practice, we can also obtain useful uncertainty estimates for optical properties recovered with a two-frequency LUT algorithm, as we demonstrate with tissue-simulating phantom and

Indexed as

(110.0113) Imaging through turbid media(170.1580) Chemometrics(170.3880) Medical and biological imaging(170.6510) Spectroscopy, tissue diagnostics(290.1990) Diffusion

Identifiers

PMID29552403
PMCPMC5854069

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.