Evidence map›Paper›PMID 29552387›Full record

ArticleBiomedical optics express2018

Holographic line field en-face OCT with digital adaptive optics in the retina

Laurin Ginner, Tilman Schmoll, Abhishek Kumar, Matthias Salas, Nastassia Pricoupenko, Lara M Wurster, Rainer A Leitgeb

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
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  7. Review
  8. Scattering oblique plane microscopy forBiomedical optics express · 2021
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  10. Recent advances in infrared imagers: toward thermodynamic and quantum limits of photon sensitivity.Reports on progress in physics. Physical Society (Great Britain) · 2020
    Article
  11. Article
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  15. 250 kHz, 1.5 µm resolution SD-OCT forBiomedical optics express · 2018
    Article
  16. Biomedical optics express · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Laurin GinnerCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria.
Tilman SchmollCarl Zeiss Meditec, Dublin, USA.
Abhishek KumarCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria.
Matthias SalasCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria.
Nastassia PricoupenkoCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria.
Lara M WursterCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria.
Rainer A LeitgebCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria.
Medical University of Vienna · ATCarl Zeiss (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We demonstrate a high-resolution line field en-face time domain optical coherence tomography (OCT) system using an off-axis holography configuration. Line field en-face OCT produces high speed en-face images at rates of up to 100 Hz. The high frame rate favors good phase stability across the lateral field-of-view which is indispensable for digital adaptive optics (DAO). Human retinal structures are acquired in-vivo with a broadband light source at 840 nm, and line rates of 10 kHz to 100 kHz. Structures of different retinal layers, such as photoreceptors, capillaries, and nerve fibers are visualized with high resolution of 2.8 µm and 5.5 µm in lateral directions. Subaperture based DAO is successfully applied to increase the visibility of cone-photoreceptors and nerve fibers. Furthermore, en-face Doppler OCT maps are generated based on calculating the differential phase shifts between recorded lines.

Indexed as

(110.0180) Microscopy(110.4500) Optical coherence tomography

Identifiers

PMID29552387
PMCPMC5854052
OpenAlexW2784054904

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.