ArticleCase reports in pathology2018
Primary Diffuse Large B Cell Lymphoma Mimicking Hyperplastic Reactive Lesion (Lymphoma of the Oral Cavity).
Article in Case reports in pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Comprehensive clinicopathological evaluation of malignant localized gingival enlargements in the Thai population.Biomedical reports · 2026Article
- Intraoral Extranodal Natural Killer Cell/T-Cell Lymphoma of the Hard Palate.Case reports in dentistry · 2023Article
- Primary extra-nodal non-Hodgkin's lymphoma affecting mandibular bone: a case report.The Pan African medical journal · 2022Article
- Primary diffuse large B-cell lymphoma of the mandible.Autopsy & case reportsArticle
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
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Abstract
objectiveTo report a case of a challenging oral diagnosis involving a primary diffuse large B cell lymphoma of the oral cavity mimicking a hyperplastic reactive lesion. CASE REPORT: A 72-year-old male patient was referred to the Department of Stomatology presenting a proliferative nodular lesion in the anterior region of the mandible involving the anterior teeth. The clinical examination revealed anterior teeth affected by periodontal disease, suggesting the nodular cession hyperplastic reaction. Incisional biopsy was performed under local anesthesia. The histopathological examination revealed a diffuse proliferation of atypical large lymphoid cells. The tumor cells showed immunopositivity for CD20 and Ki67 (100%) and negativity for CD3, CD30, and CD15. The diagnosis of diffuse large B cell lymphoma was established. The patient underwent chemotherapy and progressed to death after nine months.
conclusionLymphomas of the oral cavity are rare and may have nonspecific clinical features, mimicking inflammatory and reactive lesions. Therefore, a detailed clinical evaluation associated with histopathological and immunohistochemical analysis should be performed to enable early and accurate diagnoses in suspected oral lesions.
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