Evidence map›Paper›PMID 29552152›Full record

ArticleOncology letters2018

Effects of TIN2 on telomeres and chromosomes in the human gastric epithelial cell line GES-1.

Fan Fu, Hua Hu, Shuai Yang, Xiaoqiu Liang

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Fan FuCancer Research Institute, Key Laboratory of Tumor Cellular and Molecular Pathology, College of Hunan, University of South China, Hengyang, Hunan 421001, P.R. China.
Hua HuDepartment of Pathology, The Second Affiliated Hospital, University of South China, Hengyang, Hunan 421001, P.R. China.
Shuai YangDepartment of Pathology, The First Affiliated Hospital, University of South China, Hengyang, Hunan 421001, P.R. China.
Xiaoqiu LiangCancer Research Institute, Key Laboratory of Tumor Cellular and Molecular Pathology, College of Hunan, University of South China, Hengyang, Hunan 421001, P.R. China.
University of South China · CNHunan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TERF1-interacting nuclear factor 2 (TIN2) is a key member of the protein complexes that protect telomeres. TIN2 contributes an important role in biological processes. In a previous study by the present authors, an association was reported between high TIN2 protein expression and gastric cancer. Therefore, it was hypothesized that abnormal TIN2 expression may cause the development of malignancies, including, gastric carcinomas. To investigate this hypothesis, the present study employed peptide nucleic acid fluorescence

Indexed as

chromosome aberrationGES-1 cellstelomere dysfunction induced-fociTERF1-interacting nuclear factor 2

Identifiers

PMID29552152
PMCPMC5840751
OpenAlexW2785968477

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.