Evidence map›Paper›PMID 29552105›Full record

ArticleOncology letters2018

Enhanced radiation effect on SMCC7721 cells through endoplasmic reticulum stress induced by C225-GNPs

Chuandong Zhu, Lixue Wang, Yang Cai, Guoxiang Wang, Hanfeng Xu, Yuan Wan, Qin Zheng

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Chuandong ZhuDepartment of Oncology, The Second Hospital of Nanjing Affiliated to Medical School of Southeast University, Nanjing, Jiangsu 210003, P.R. China.
Lixue WangDepartment of Oncological Radiotherapy, The Second Hospital of Nanjing Affiliated to Medical School of Southeast University, Nanjing, Jiangsu 210003, P.R. China.
Yang CaiDepartment of Oncology, Xishan People's Hospital, Wuxi, Jiangsu 214011, P.R. China.
Guoxiang WangNanjing Zetect Bioscience Incorporated, Nanjing, Jiangsu 210061, P.R. China.
Hanfeng XuDepartment of Oncology, The Second Hospital of Nanjing Affiliated to Medical School of Southeast University, Nanjing, Jiangsu 210003, P.R. China.
Yuan WanDepartment of Biomedical Engineering, Pennsylvania State University, State College, PA 16801, USA.
Qin ZhengDepartment of Oncology, The Second Hospital of Nanjing Affiliated to Medical School of Southeast University, Nanjing, Jiangsu 210003, P.R. China.
Southeast University · CNPennsylvania State University · USWuxi People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The high atomic number of gold nanoparticles (GNPs) enables them to offer potential as practical and efficient radiosensitizing agents for cancer radiotherapy applications. In the present study, it was demonstrated that GNPs can significantly modulate the irradiation response of hepatocellular carcinoma (HCC) cells

Indexed as

cetuximabendothelial network stressgold nanoparticleradiosensitizationSMCC7721 cell

Identifiers

PMID29552105
PMCPMC5840568
OpenAlexW2792376417

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.