ArticleJournal of Indian Society of Periodontology
Comparison of anti-plaque and anti-gingivitis effect of curcumin and chlorhexidine mouth rinse in the treatment of gingivitis: A clinical and biochemical study.
Article in Journal of Indian Society of Periodontology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Effect of Adjunctive Use of Commercial Daily Mouthwashes on Periodontal Health: An Umbrella Review.Journal of clinical periodontology · 2026Pooled it
- The Effects of Curcumin in the Treatment of Gingivitis: A Systematic Review of Clinical Trials.Advances in experimental medicine and biology · 2021Pooled it
- N-acetyl cysteine versus chlorhexidine mouthwashes in prevention and treatment of experimental gingivitis: a randomized, triple-blind, placebo-controlled clinical trial.Clinical oral investigations · 2019Trial
- Comparison of hyaluronic acid, chlorhexidine and persica during SRP.Bioinformation · 2026Article
- Comparative Evaluation of Antimicrobial Efficacy of Aqueous and Alcoholic Formulations of Triphala and Curcumin Mouthrinses against Periodontal Pathogens.Journal of pharmacy & bioallied sciences · 2025Article
- Mitochondrial Dysfunction in Diabetic Periodontitis: Mechanisms and Therapeutic Potential.Journal of inflammation research · 2025Review
- Article
- A Randomized Clinical Study of a Curcumin and Melatonin Toothpaste Against Periodontal Bacteria.Biomedicines · 2024Article
- The Antimicrobial Activity of Curcumin and Xanthohumol on Bacterial Biofilms Developed over Dental Implant Surfaces.International journal of molecular sciences · 2023Article
- Effect of curcumin, betadine and chlorhexidine in gingival wound healing.Bioinformation · 2023Article
- Host Response Modulation Therapy in the Diabetes Mellitus-Periodontitis Conjuncture: A Narrative Review.Pharmaceutics · 2022Review
- Curcumin as a Natural Approach of Periodontal Adjunctive Treatment and Its Immunological Implications: A Narrative Review.Pharmaceutics · 2022Review
- Exploring the Potential of Natural Product-Based Nanomedicine for Maintaining Oral Health.Molecules (Basel, Switzerland) · 2022Review
- Anti-Inflammatory Efficacy of Curcumin as an Adjunct to Non-Surgical Periodontal Treatment: A Systematic Review and Meta-Analysis.Frontiers in pharmacology · 2022Review
- Myrrh mixed with silver nanoparticles demonstrates superior antimicrobial activity againstThe Saudi dental journal · 2021Article
- The effect of curcumin as an adjunct in the treatment of chronic periodontitis: A systematic review and meta-analysis.The Saudi dental journal · 2021Review
- From Simple Mouth Cavities to Complex Oral Mucosal Disorders-Curcuminoids as a Promising Therapeutic Approach.ACS pharmacology & translational science · 2021Review
- Recent Development of Active Ingredients in Mouthwashes and Toothpastes for Periodontal Diseases.Molecules (Basel, Switzerland) · 2021Review
- Effect of Turmeric Concentrations on the Rate of Growth of Oral Bacteria-An In-Vitro Study.Dentistry journal · 2021Article
- The Effect of Herbal Medicine and Natural Bioactive Compounds on Plasma Adiponectin: A Clinical Review.Advances in experimental medicine and biology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo evaluate and compare the effect of curcumin (CMN) mouth rinse with chlorhexidine (CHX) mouth rinse on clinical parameters and reactive oxygen metabolites (ROM) levels in participants with chronic gingivitis. MATERIALS AND
methodsThirty plaque-induced generalized chronic gingivitis participants were randomly assigned to three groups - Group I (control/saline), Group II (CHX), and Group III (CMN), respectively. Baseline plaque index (PI), gingival index (GI), and salivary ROM were estimated, and oral prophylaxis was done. The parameters were recorded and evaluated again at the end of 4 weeks.
resultsOverall, the three groups have shown a significant reduction in PI, GI, and ROM levels at the end of 4 weeks. However, on intragroup comparison, only CMN group have shown significant reduction in ROM levels at the end of 4 weeks (
conclusionCMN mouth rinse can be considered as an alternative antigingivitis agent to CHX because of its anti-inflammatory and antioxidant properties.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.