ReviewSeminars in cell & developmental biology2019
Flying under the radar: Histoplasma capsulatum avoidance of innate immune recognition.
Review in Seminars in cell & developmental biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed.
- How Histoplasma Evades the Human Immune System.Acta medica academica · 2025Review
- Revealing pathogenesis-associated metabolites inmSystems · 2025Article
- Microbial adaptive pathogenicity strategies to the host inflammatory environment.FEMS microbiology reviews · 2025Review
- Review
- Genotypic diversity, virulence, and molecular genetic tools inMicrobiology and molecular biology reviews : MMBR · 2024Review
- Design of a Multi-Epitope Vaccine againstJournal of fungi (Basel, Switzerland) · 2024Article
- Insights on Covid-19 with superimposed pulmonary histoplasmosis: The possible nexus.Immunity, inflammation and disease · 2023Review
- Targeted gene deletions in the dimorphic fungal pathogenmSphere · 2023Article
- Comparative Genomics ofJournal of fungi (Basel, Switzerland) · 2023Article
- Fungal resilience and host-pathogen interactions: Future perspectives and opportunities.Parasite immunology · 2023Review
- Antifungal Susceptibility Testing and Drug Discovery in the Dimorphic Fungus Histoplasma Capsulatum.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Pathogenicity & virulence ofVirulence · 2022Review
- Article
- Antifungal Encapsulated into Ligand-Functionalized Nanoparticles with High Specificity for Macrophages.Pharmaceutics · 2022Article
- Genome-scale CRISPR screening reveals that C3aR signaling is critical for rapid capture of fungi by macrophages.PLoS pathogens · 2022Article
- Challenges in Serologic Diagnostics of Neglected Human Systemic Mycoses: An Overview on Characterization of New Targets.Pathogens (Basel, Switzerland) · 2022Review
- Considerations about the Geographic Distribution ofApplied and environmental microbiology · 2022Review
- Key thermally dimorphic fungal pathogens: shaping host immunity.Open biology · 2022Review
- Deletion of the Stress Response GeneJournal of fungi (Basel, Switzerland) · 2021Article
- In vitro infection models to study fungal-host interactions.FEMS microbiology reviews · 2021Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The dimorphic fungal pathogen Histoplasma capsulatum takes advantage of the innate immune system, utilizing host macrophages as a proliferative niche while largely avoiding stimulation of signaling host receptors. As a result, innate immune cells are unable to control H. capsulatum on their own. Not all host phagocytes respond to H. capsulatum in the same way, with neutrophils and dendritic cells playing important roles in impeding fungal growth and initiating a protective T
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.