Evidence map›Paper›PMID 29551455›Full record

ReviewDrug discovery today2018

A tumor multicomponent targeting chemoimmune drug delivery system for reprograming the tumor microenvironment and personalized cancer therapy.

Samaresh Sau, Katyayani Tatiparti, Hashem O Alsaab, Sushil K Kashaw, Arun K Iyer

Abstract readReview
In one paragraph

Review in Drug discovery today, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Samaresh SauUse-inspired Biomaterials & Integrated Nano Delivery (U-BiND) Systems Laboratory, Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA. Electronic address: samaresh.sau@wayne.edu.
Katyayani TatipartiUse-inspired Biomaterials & Integrated Nano Delivery (U-BiND) Systems Laboratory, Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.
Hashem O AlsaabUse-inspired Biomaterials & Integrated Nano Delivery (U-BiND) Systems Laboratory, Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA; Department of Pharmaceutics and Pharmaceutical Technology, College of Pharmacy, Taif University, Taif, Saudi Arabia.
Sushil K KashawDepartment of Pharmaceutical Sciences, Dr Harisingh Gour Central University, Sagar, MP 470003, India.
Arun K IyerUse-inspired Biomaterials & Integrated Nano Delivery (U-BiND) Systems Laboratory, Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA; Molecular Imaging Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA. Electronic address: arun.iyer@wayne.edu.

Funding

Targeted Platinates/siRNA Combination Therapy for Resistant Lung CancerR21CA179652 · NCI · NORTHEASTERN UNIVERSITY · PI AMIJI, MANSOOR M., IYER, ARUN · 2014 to 2015
$372k
NCI NIH HHS R21 CA179652
6 · The paper itself

Abstract

Nanoparticle library engineered with tunable size, shape, and geometry will provide a better idea of targeting multicomponent of tumor microenvironment consisting of epithelial cells, tumor hypoxia, tumor immune cells and angiogenic blood vessels.

Indexed as

Drug CarriersTumor MicroenvironmentAnimalsAntineoplastic Agents, ImmunologicalClinical Decision-MakingDrug Delivery SystemsHumansImmunoconjugatesNanoparticlesNeoplasmsNeovascularization, PathologicPrecision MedicineTheranostic NanomedicineTumor HypoxiaAntineoplastic Agents, ImmunologicalDrug CarriersImmunoconjugates

Identifiers

PMID29551455
PMCPMC6046265

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.