Evidence map›Paper›PMID 29551311›Full record

ArticleThe Journal of pediatrics2018

Validity of Body Mass Index as a Measure of Adiposity in Infancy.

Katherine A Bell, Carol L Wagner, Wei Perng, Henry A Feldman, Roman J Shypailo, Mandy B Belfort

Registry-linked trialAbstract read
In one paragraph

Article in The Journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00412074 (Establishing the Vitamin D Requirements During Lactation), which is not on this map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00412074 phase3completednot on this map

Establishing the Vitamin D Requirements During Lactation

TypeinterventionalSponsorMedical University of South CarolinaRan2006 to 2012Enrolled460ConditionsVitamin D DeficiencyArms400 IU Vitamin D3 (cholecalciferol), 2400 IU Vitamin D3 (cholecalciferol), 6400 IU Vitamin D3 (cholecalciferol)
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  13. Infant body composition: A comprehensive overview of assessment techniques, nutrition factors, and health outcomes.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katherine A BellDepartment of Pediatric Newborn Medicine, Brigham & Women's Hospital, Boston, MA. Electronic address: kbell7@partners.org.
Carol L WagnerDepartment of Pediatrics, Medical University of South Carolina, Charleston, SC.
Wei PerngDepartments of Nutritional Sciences and Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI.
Henry A FeldmanClinical Research Center, Boston Children's Hospital, Boston, MA.
Roman J ShypailoUSDA/ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston, TX.
Mandy B BelfortDepartment of Pediatric Newborn Medicine, Brigham & Women's Hospital, Boston, MA.

Funding

South Carolina Clinical & Translational Research Institute (SCTR)UL1TR001450 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T., FLUME, PATRICK A · 2015 to 2024
$41.1M
ZINC AND COPPER METABOLISM IN COLLAGEN DISORDERSM01RR001070 · NCRR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI REVES, JOSEPH G · 1985 to 2009
$16.3M
South Carolina Clinical & Translational Research Institute (SCTR)UL1TR000062 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T. · 2012 to 2014
$9.4M
Evaluation of Vitamin D Requirements During PregnancyR01HD043921 · NICHD · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI HOLLIS, BRUCE W · 2003 to 2007
$2.6M
NCATS NIH HHS UL1 TR000062NCATS NIH HHS UL1 TR001450NCRR NIH HHS M01 RR001070NICHD NIH HHS R01 HD043921
6 · The paper itself

Abstract

objectivesTo assess the validity of body mass index (BMI) and age- and sex-standardized BMI z-score (BMIZ) as surrogates for adiposity (body fat percentage [BF%], fat mass, and fat mass index [kg/m STUDY

designWe performed a secondary analysis of 447 full-term infants in a previous trial of maternal vitamin D supplementation during lactation. Study staff measured infant anthropometrics and assessed body composition with dual-energy x-ray absorptiometry at 1, 4, and 7 months of age. We calculated Spearman correlations (r

resultsInfants (N = 447) were 52% male, 38% white, 31% black, and 29% Hispanic. The BMIZ was moderately correlated with BF% (r

conclusionsBMIZ is moderately correlated with adiposity in infancy. Changes in BMIZ are a poor indicator of adiposity changes in later infancy. BMI and BMIZ are limited as surrogates for adiposity and especially adiposity changes in infancy.

trial registrationClinicalTrials.gov: NCT00412074.

Indexed as

AdiposityBody Mass IndexAnthropometryBirth WeightBody CompositionDietary SupplementsFemaleHumansInfantInfant, NewbornLactationMalePediatricsRandomized Controlled Trials as TopicVitamin DVitamin Dbody compositioninfant

Identifiers

PMID29551311
PMCPMC5924641

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.