Evidence map›Paper›PMID 29551101›Full record

SynthesisPublic health nutrition2018

Association between fish consumption and risk of dementia: a new study from China and a systematic literature review and meta-analysis.

Aishat T Bakre, Ruoling Chen, Ranjit Khutan, Li Wei, Tina Smith, Gordon Qin, Isaac M Danat, Weiju Zhou, Peter Schofield, Angela Clifford and 4 more

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Public health nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 7 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 7 syntheses or guidelines pooled it, 66 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 3 countries.

Aishat T Bakre1Faculty of Education,Health and Wellbeing,University of Wolverhampton,Wolverhampton WV1 1DT,UK.
Ruoling Chen1Faculty of Education,Health and Wellbeing,University of Wolverhampton,Wolverhampton WV1 1DT,UK.
Ranjit Khutan1Faculty of Education,Health and Wellbeing,University of Wolverhampton,Wolverhampton WV1 1DT,UK.
Li Wei2Department of Practice and Policy,University College London,London,UK.
Tina Smith1Faculty of Education,Health and Wellbeing,University of Wolverhampton,Wolverhampton WV1 1DT,UK.
Gordon Qin3Royal Wolverhampton NHS Trust,Wolverhampton,UK.
Isaac M Danat1Faculty of Education,Health and Wellbeing,University of Wolverhampton,Wolverhampton WV1 1DT,UK.
Weiju Zhou1Faculty of Education,Health and Wellbeing,University of Wolverhampton,Wolverhampton WV1 1DT,UK.
Peter Schofield4Department of Primary Care and Public Health Sciences,King's College London,London,UK.
Angela Clifford1Faculty of Education,Health and Wellbeing,University of Wolverhampton,Wolverhampton WV1 1DT,UK.
Jiaji Wang5Department of Preventive Medicine, School of Public Health,Guangzhou Medical University,Guangzhou 510182,People's Republic of China.
Arpana Verma6Division of Population Health,Health Services Research and Primary Care,Faculty of Biology,Medicine and Health,University of Manchester,Manchester,UK.
Cuilin Zhang7Epidemiology Branch,Division of Intramural Population Health Research,Eunice Kennedy Shriver National Institute of Child Health and Human Development,National Institutes of Health,Bethesda,MD, USA.
Jindong Ni8Department of Epidemiology and Biostatistics,Guangdong Medical University,Dongguan, Guangdong,People's Republic of China.
University of Wolverhampton · GBGuangdong Medical College · CNGuangzhou Medical University · CNKing's College London · GBNational Institutes of Health · USThe Royal Wolverhampton NHS Trust · GBUniversity College London · GBUniversity of Manchester · GB

Funding

Medical Research Council G106/1249
6 · The paper itself

Abstract

objectiveTo assess the association of fish consumption with risk of dementia and its dose-response relationship, and investigate variations in the association among low-, middle- and high-income countries.

designA new community-based cross-sectional study and a systematic literature review.SettingsUrban and rural communities in China; population-based studies systematically searched from worldwide literature. SUBJECTS: Chinese adults aged ≥60 years in six provinces (n 6981) took part in a household health survey of dementia prevalence and risk factors. In addition, 33 964 participants from eleven published and eligible studies were included in the systematic review and meta-analysis.

resultsIn the new study in China, 326 participants were diagnosed with dementia (4·7 %); those who consumed any amount of fish in the past two years v. those who consumed no fish had reduced risk of dementia (adjusted OR=0·73, 95 % CI 0·64, 0·99), but the dose-response relationship was not statistically significant. The meta-analysis of available data from the literature and the new study showed relative risk (RR) of dementia of 0·80 (95 % CI 0·74, 0·87) for people with fish consumption; the impact was similar among countries with different levels of income. Pooled dose-response data revealed RR (95 % CI) of 0·84 (0·72, 0·98), 0·78 (0·68, 0·90) and 0·77 (0·61, 0·98) in people with low, middle and high consumption of fish, respectively. Corresponding figures for Alzheimer's disease were 0·88 (0·74, 1·04), 0·79 (0·65, 0·96) and 0·67 (0·58, 0·78), respectively.

conclusionsGreater consumption of fish is associated with a lower risk of dementia. Increasing fish consumption may help prevent dementia worldwide regardless of income level.

Indexed as

FishesSeafoodAnimalsChinaCross-Sectional StudiesDementiaDietHumansMiddle AgedAlzheimer’s diseaseDementiaFish consumption

Identifiers

PMID29551101
PMCPMC10260768
OpenAlexW2793787902

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.