ArticleInternational ophthalmology2019
Clinical risk factors associated with intraoperative floppy iris syndrome: a prospective study.
Article in International ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 37 citations in OpenAlex.
- Intraoperative floppy iris syndrome in cataract surgery: effects of opium use.International ophthalmology · 2026Article
- Risk factors for occurrence of reverse pupillary block after intraocular lens fixation surgery.Journal of cataract and refractive surgery · 2026Observational
- Investigating the impact of age and sex on cataract surgery complications and outcomes.Scientific reports · 2025Article
- Article
- Intraoperative Iris Behavior during Phacoemulsification Maneuvers in Rabbits Treated with Selective α1-Blocker, 5α-Reductase Inhibitor, or Anxiolytic Medication.Journal of personalized medicine · 2024Article
- Prospective analysis of anatomic features predisposing patients to intraoperative floppy iris syndrome.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Iris color as a predictive factor for intraoperative floppy iris syndrome.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Floppy iris syndrome associated with specific medication intake: A narrative review.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2023Review
- Silodosin as a predisposing factor of intraoperative floppy iris syndrome (IFIS): an observational propensity score-matching cohort study.International ophthalmology · 2022Observational
- Risk of intraoperative floppy iris syndrome among selective alpha-1 blockers-A consistency model of 6,488 cases.Frontiers in medicine · 2022Article
- Intraoperative floppy iris syndrome: an updated review of literature.International ophthalmology · 2021Review
- Preoperative ocular characteristics predicting the development of intraoperative floppy iris syndrome regardless of alpha-antagonist exposure status.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021Article
- Evaluation of static and dynamic Pupillometry changes in men using Silodosin for benign prostatic hypertrophy.BMC ophthalmology · 2021Article
- Predictive value of pupillography on intraoperative floppy iris syndrome in preoperative period.International journal of ophthalmology · 2021Article
- A narrative review of intraoperative floppy iris syndrome: an update 2020.Annals of translational medicine · 2020Review
- Intraoperative Floppy Iris Syndrome: Updated Perspectives.Clinical ophthalmology (Auckland, N.Z.) · 2020Review
- Risk factors for intraoperative floppy iris syndrome in female cataract patients: The roles of ARB medication and diabetes mellitus.Advances in ophthalmology practice and researchArticle
- Intraoperative Floppy Iris Syndrome Induced by Tamsulosin: The Risk and Preventive Strategies.Middle East African journal of ophthalmologyReview
- Pathophysiology of intraoperative floppy iris syndrome: An unsettled debate.Survey of ophthalmologyReview
- Finasteride and Floppy Iris Syndrome: What Role Can the Dermatologist Play?International journal of trichologyArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the incidence of and factors associated with intraoperative floppy iris syndrome (IFIS) in patients undergoing cataract phacoemulsification.
methodsIn total, 319 eyes of 319 patients who underwent phacoemulsification with implantation of an intraocular lens (IOL) into the posterior chamber were included in this study. Direct injection of epinephrine into the anterior chamber was performed in all cases. The following patient information was collected: gender, age, axial length of the eye, presence of pseudoexfoliation syndrome, glaucoma, diabetes mellitus, hypertension, current use of medications including alpha1 adrenergic receptor antagonists (alpha1-ARAs), finasteride, and benzodiazepines, duration of intake of alpha1-ARAs and finasteride, and duration of the surgery. Patients were classified as IFIS or non-IFIS after the surgery. Univariate and multivariate logistic regression analyses were performed.
resultsThe overall incidence of IFIS was 9.09% (29/319 eyes). The multivariate analysis revealed that tamsulosin use (P = 0.004), finasteride use (P = 0.014), and increasing age (P = 0.006) were significantly associated with IFIS. Male gender and benzodiazepine use were significantly associated with IFIS in the univariate analysis, but not in the multivariate analysis. The non-selective alpha1-ARA doxazosin was not found to be associated with IFIS.
conclusionsThe findings suggest that finasteride use and aging are risk factors for IFIS and confirm the association of tamsulosin use with IFIS. Further, doxazosin appears to be a relatively safe drug with respect to the occurrence of IFIS.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.