Evidence map›Paper›PMID 29550920›Full record

Trial reportEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2018

Analyzing eustachian tube function in patients with symptoms of chronical Eustachian tube dysfunction by pressure chamber measurements.

Moritz F Meyer, Christine Korthäuer, Stefanie Jansen, Karl-Bernd Hüttenbrink, Dirk Beutner

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Assessment of the Eustachian tube: a review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Review
  4. Correlation of Eustachian tube function with the results of type 1 tympanoplasty: a prospective study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Moritz F MeyerDepartment of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine, University of Cologne, Kerpener Straße 62, 50937, Cologne, Germany. moritz.meyer@uk-koeln.de.
Christine KorthäuerDepartment of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine, University of Cologne, Kerpener Straße 62, 50937, Cologne, Germany.
Stefanie JansenDepartment of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine, University of Cologne, Kerpener Straße 62, 50937, Cologne, Germany.
Karl-Bernd HüttenbrinkDepartment of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine, University of Cologne, Kerpener Straße 62, 50937, Cologne, Germany.
Dirk BeutnerDepartment of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine, University of Cologne, Kerpener Straße 62, 50937, Cologne, Germany.
University of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe determination of Eustachian tube dysfunction (ETD) subtypes in daily routines is based on symptoms of the patient, otoscopy, nasopharyngoscopy, tympanometry, pure tone audiometry, and Valsalva's test, even though this clinical assessment is often not sufficient to clearly diagnose the subtype. In the study, we have evaluated the possibility of the determination of different subtypes of ETD by pressure chamber measurements.

methodsIn a single-person pressure chamber, we exposed 17 patients to pressure increases and decreases. The pressure profile of the continuous impedance of each tympanic membrane during the 5-min lasting measurement and the Eustachian tube (ET) pressure equilibration function reflecting parameters-ET opening pressure (ETOP), ET opening duration (ETOD), ET closing pressure (ETCP), and ET opening frequency (ETOF)-were documented and analyzed.

resultsBy interpretation of the pattern of the continuous impedance of the tympanic membrane, we could relate patients to a subtype of ETD. Clearly identified by pressure chamber-based measurements could be patients with patulous ETD (n = 2) and baro-challenged-induced ETD (n = 4). The remaining 11 patients were classified as ETD not further classified. Patients diagnosed as patulous ETD did not show a pressure response on the tympanic membrane during the phases of pressure increase and decrease. In patients with baro-challenged-induced ETD, the measurement had to be interrupted due to the development of otalgia during progressive pressure increase as a result of insufficient possibility to equalize pressure variations.

conclusionsPressure chamber-based measurements enable an objective and safe dynamic testing of the ET pressure equalization function in patients with ETD. In addition, via continuous impedance measurement, it is possible to identify patients with patulous ETD and baro-challenge-induced ETD. These results are a relevant preliminary work to identify and assess patients for different therapy options.

Indexed as

Diagnostic Techniques, OtologicalPressureAdolescentAdultChildEar DiseasesEustachian TubeFemaleHumansMaleMiddle AgedProspective StudiesYoung AdultContinuous impedanceDiagnosticsEustachian tubeOpening durationOpening pressurePressure chamber

Identifiers

PMID29550920
OpenAlexW2793935933

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.