Evidence map›Paper›PMID 29550914›Full record

ArticleInternational orthopaedics2018

Hip osteonecroses treated with calcium sulfate-calcium phosphate bone graft substitute have different results according to the cause of osteonecrosis: alcohol abuse or corticosteroid-induced.

Andrzej Sionek, Adam Czwojdziński, Jacek Kowalczewski, Tomasz Okoń, Dariusz Marczak, Marcin Sibiński, Marcin Złotorowicz, Jarosław Czubak

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in International orthopaedics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

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  17. Global urinary metabolic profiling of the osteonecrosis of the femoral head based on UPLC-QTOF/MS.Metabolomics : Official journal of the Metabolomic Society · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Andrzej SionekDepartment of Orthopaedics, Pediatric Orthopaedics and Traumatology, Medical Centre of Postgraduate Education, Warsaw-Otwock, ul. Konarskiego 13, 05-400, Otwock, Poland.
Adam CzwojdzińskiDepartment of Orthopaedics, Pediatric Orthopaedics and Traumatology, Medical Centre of Postgraduate Education, Warsaw-Otwock, ul. Konarskiego 13, 05-400, Otwock, Poland.
Jacek KowalczewskiOrthopaedic Department, Medical Centre of Postgraduate Education, Warsaw-Otwock, ul. Konarskiego 13, 05-400, Otwock, Poland.
Tomasz OkońOrthopaedic Department, Medical Centre of Postgraduate Education, Warsaw-Otwock, ul. Konarskiego 13, 05-400, Otwock, Poland.
Dariusz MarczakOrthopaedic Department, Medical Centre of Postgraduate Education, Warsaw-Otwock, ul. Konarskiego 13, 05-400, Otwock, Poland.
Marcin SibińskiDepartment of Orthopedics and Pediatric Orthopedics, Medical University of Lodz, ul. Pomorska 251, 92-213, Łódź, Poland. sibinskimar@gmail.com.
Marcin ZłotorowiczDepartment of Orthopaedics, Pediatric Orthopaedics and Traumatology, Medical Centre of Postgraduate Education, Warsaw-Otwock, ul. Konarskiego 13, 05-400, Otwock, Poland.
Jarosław CzubakDepartment of Orthopaedics, Pediatric Orthopaedics and Traumatology, Medical Centre of Postgraduate Education, Warsaw-Otwock, ul. Konarskiego 13, 05-400, Otwock, Poland.
Medical University of Lodz · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of the study was to assess the factors influencing the final results of treatment of the femoral head osteonecrosis (ONFH) with core decompression and bone substitute grafting. The special interest was focused on comparison between alcohol- and steroid-induced ONFHs. MATERIAL AND

methodsIn this prospective study, a total of 53 patients (58 hips) in the mean age of 35.5 years were included: 29 had a history of alcohol use (32 hips) and 24 of steroid use (26 hips). The mean follow-up was 4.2 years (minimum 3 years).

resultsAt last follow-up, significant improvements were noted in the Harris Hip Score (HHS) (mean 44.0 vs 55.9 points, p < 0.00002) and VAS scores (mean 7.0 vs 5.8 points, p < 0.0002) for the whole ONFH cohort, comparing to pre-operative status. The degree of improvement did not differ between Ficat and Arlet grade II and grade III (mean 14.9 vs 6.2 points, respectively, p = 0.1). No change was found between the final and initial results in this group in the steroid group (HHS mean 42.2 vs 45.5 points, p = 0.5 and VAS mean 6.8 vs 6.5 points, p = 0.5), but the improvement was noted in the alcohol group (HHS mean 45.5 vs 64.4 points, p < 0.0001; VAS mean 7.1 vs 5.2 points, p < 0.0001) comparing to pre-operative status.

conclusionsPresented treatment of ONFH significantly improves hip function, offers pain reduction, and gives similar functional improvement for hips scoring grade II and III on the Ficat and Arlet scale. A good response to operative treatment is seen in patients with alcohol-induced ONFH, but not in those with steroid-induced ONFH.

Indexed as

AdolescentAdultAlcoholismBone SubstitutesBone TransplantationCalcium PhosphatesCalcium SulfateDecompression, SurgicalFemaleFemur HeadFemur Head NecrosisGlucocorticoidsHumansMaleMiddle AgedPain MeasurementBone Substitutescalcium phosphateCalcium PhosphatesCalcium SulfateGlucocorticoidsAvascular necrosis of femoral headCalcium phosphateCalcium sulfateMini-invasive treatmentRehabilitation

Identifiers

PMID29550914
OpenAlexW2789698593

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.