Evidence map›Paper›PMID 29550912›Full record

ArticleInternational orthopaedics2018

Is osteonecrosis due to systemic lupus erythematosus associated with increased risk of complications following total hip arthroplasty?

Dennis Q Chen, Jourdan M Cancienne, Brian C Werner, Quanjun Cui

Abstract read
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In one paragraph

Article in International orthopaedics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dennis Q ChenDepartment of Orthopaedic Surgery, University of Virginia Health System, 400 Ray C. Hunt Drive, Suite 330, Charlottesville, VA, 22903, USA.
Jourdan M CancienneDepartment of Orthopaedic Surgery, University of Virginia Health System, 400 Ray C. Hunt Drive, Suite 330, Charlottesville, VA, 22903, USA.
Brian C WernerDepartment of Orthopaedic Surgery, University of Virginia Health System, 400 Ray C. Hunt Drive, Suite 330, Charlottesville, VA, 22903, USA.
Quanjun CuiDepartment of Orthopaedic Surgery, University of Virginia Health System, 400 Ray C. Hunt Drive, Suite 330, Charlottesville, VA, 22903, USA. qc4q@hscmail.mcc.virginia.edu.ORCID http://orcid.org/0000-0003-4285-4488
University of Virginia Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAs the medical treatment of systemic lupus erythematosus (SLE) has evolved, the rate of total hip arthroplasty (THA) in SLE patients has increased, with osteonecrosis (ON) being the primary indication for arthroplasty in a quarter of cases. Comparative literature evaluating outcomes following THA for patients with SLE and ON versus patients with non-SLE-related ON or patients with osteoarthritis (OA) is limited. The goal of the present study was to investigate the current trend in SLE patients undergoing THA and compare complications following THA for ON with SLE, ON without SLE, and OA.

methodsThe PearlDiver patient records database ( www.pearldiverinc.com , Colorado Springs, CO), a for-fee insurance-based patient records database, was utilized for this study. Two hundred forty-four patients who underwent THA for ON associated with SLE were identified and compared to control cohorts of 7836 patients with ON without SLE and 64,235 patients with OA using a multivariate analysis.

resultsWe found patients with SLE undergoing THA for ON experienced lower rates of infection and revision but a higher rate of medical complications compared to patients undergoing THA for non-SLE ON diagnoses. Patients with SLE undergoing THA for ON experienced decreased rates of infection but increased rates of transfusion and medical complications compared to patients undergoing THA for OA.

conclusionsOur data demonstrate that THA can be safely performed on SLE patients with ON without significantly increased morbidity compared to that in patients with non-SLE-associated ON or patients with OA.

Indexed as

AgedArthroplasty, Replacement, HipDatabases, FactualFemaleFemur Head NecrosisHumansLupus Erythematosus, SystemicMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesRisk FactorsTreatment OutcomeOsteonecrosisSystemic lupus erythematosusTotal hip arthroplasty

Identifiers

PMID29550912
OpenAlexW2789254095

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.