ArticleHellenic journal of nuclear medicine
Is there an association between hibernating myocardium and left ventricular mechanical dyssynchrony in patients with myocardial infarction?
Article in Hellenic journal of nuclear medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 10 citations in OpenAlex.
- Left ventricular mechanical dyssnchrony: A potential new marker for 3-vessel CAD.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Comparison of left ventricle mechanical dyssynchrony parameters in ischemic and non-ischemic patients usingJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Incremental Value of Left Ventricular Mechanical Dyssynchrony Assessment by Nitrogen-13 Ammonia ECG-Gated PET in Patients With Coronary Artery Disease.Frontiers in cardiovascular medicine · 2021Article
- Left ventricular mechanical dyssynchrony analzyed by Tc-99m sestamibi SPECT and F-18 FDG PET in patients with ischemic cardiomyopathy and the prognostic value.The international journal of cardiovascular imaging · 2020Article
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
objectiveLeft ventricular mechanical dyssynchrony (LVMD) is an important factor in the prognosis of patients with myocardial infarction (MI). The aim of this study is to identify the influencing factors of LVMD in MI patients by radionuclide myocardial imaging. SUBJECTS AND
methodsThis study consisted of 91 patients who had a history of definite prior MI and underwent both technetium-99m methoxyisobutylisonitrile (
resultsLeft ventricular MD was present in 37/91 (40.7%) MI patients. Hibernating myocardium (SPET/PET mismatch) and scar in patients with LVMD were significantly higher than those without LVMD (15.24±11.26% vs 4.89±5.41%, P<0.001; 11.11±9.42% vs 4.72±5.71%, P<0.001; respectively). PBW correlated with hibernating myocardium and scar (r=0.542, 0.469, P<0.001; respectively). The multivariate logistic regression analysis showed that hibernating myocardium was an independent factor of LVMD in MI patients (OR=1.110, P=0.009), and >6.5% hibernating myocardium as a threshold can be used to better discriminate LVMD. In addition, the improvement of PBW (ΔPBW) after CABG at a median follow-up time of 6 months was related with the amount of hibernating myocardium.
conclusionMyocardial infarction patients with LVMD show significantly more segments of larger amounts of hibernating myocardium and scars as compared to those without LVMD. Hibernating myocardium is independently associated with LVMD in MI patients.
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