ArticleBrain and cognition2018
Early enhanced processing and delayed habituation to deviance sounds in autism spectrum disorder.
Article in Brain and cognition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
52 citing papers in PubMed, 7 syntheses or guidelines pooled it, 86 citations in OpenAlex.
- Minimal Differences in Auditory and Visual Oddball Tasks in Autism: A Systematic Review and Meta-Analysis.Journal of autism and developmental disorders · 2026Pooled it
- Auditory Sensitivity in Autism: A Systematic Review of Mismatch Negativity and Mismatch Field Responses.Autism research : official journal of the International Society for Autism Research · 2026Pooled it
- Light and sound hypersensitivity in autism spectrum disorder: a systematic review focusing on age and gender bias.Frontiers in psychiatry · 2026Pooled it
- Systematic Review and Meta-Analysis of Mismatch Negativity in Autism: Insights Into Predictive Mechanisms.Autism research : official journal of the International Society for Autism Research · 2025Pooled it
- Oscillatory activity underlying cognitive performance in children and adolescents with autism: a systematic review.Frontiers in human neuroscience · 2024Pooled it
- Autism Spectrum Disorder and auditory sensory alterations: a systematic review on the integrity of cognitive and neuronal functions related to auditory processing.Journal of neural transmission (Vienna, Austria : 1996) · 2023Pooled it
- Cortical Auditory Processing of Simple Stimuli Is Altered in Autism: A Meta-analysis of Auditory Evoked Responses.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2021Pooled it
- Towards precision psychiatry: initial foundations and future directions.Nature reviews. Drug discovery · 2026Review
- Atypical auditory cortical processing in ADHD during early and middle childhood.Developmental cognitive neuroscience · 2026Article
- The Influence of Sensory Processing on Executive Function in Young Autistic Children.Journal of autism and developmental disorders · 2026Article
- Neural Processing of Speech Sounds in Autistic Kindergarteners as a Predictor of Reading Outcomes.Journal of autism and developmental disorders · 2026Article
- Reduced Habituation: A Key to Understanding Sensory Sensitivity in Autism.Journal of autism and developmental disorders · 2026Article
- Infant sensory gating and a developmental cascade to autistic traits and anxiety.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Attention-Dependent but not Pre-attentive Neural Markers of Auditory Change Process are Atypical in Adults With Autism Spectrum Conditions.Journal of autism and developmental disorders · 2025Article
- Visual and auditory attention in individuals with DYRK1A and SCN2A disruptive variants.Autism research : official journal of the International Society for Autism Research · 2025Article
- Auditory environments influence the link between Autistic traits and quality of life.Scientific reports · 2025Article
- How auditory processing influences the autistic profile: A review.Autism research : official journal of the International Society for Autism Research · 2024Review
- No Differences in Auditory Steady-State Responses in Children with Autism Spectrum Disorder and Typically Developing Children.Journal of autism and developmental disorders · 2024Article
- Brain Signatures of Early and Late Neural Measures of Auditory Habituation and Discrimination in Autism and Their Relationship to Autistic Traits and Sensory Overresponsivity.Journal of autism and developmental disorders · 2024Article
- Processing of auditory novelty in human cortex during a semantic categorization task.Hearing research · 2024Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Children with autism spectrum disorder (ASD) exhibit difficulties processing and encoding sensory information in daily life. Cognitive response to environmental change in control individuals is naturally dynamic, meaning it habituates or reduces over time as one becomes accustomed to the deviance. The origin of atypical response to deviance in ASD may relate to differences in this dynamic habituation. The current study of 133 children and young adults with and without ASD examined classic electrophysiological responses (MMN and P3a), as well as temporal patterns of habituation (i.e., N1 and P3a change over time) in response to a passive auditory oddball task. Individuals with ASD showed an overall heightened sensitivity to change as exhibited by greater P3a amplitude to novel sounds. Moreover, youth with ASD showed dynamic ERP differences, including slower attenuation of the N1 response to infrequent tones and the P3a response to novel sounds. Dynamic ERP responses were related to parent ratings of auditory sensory-seeking behaviors, but not general cognition. As the first large-scale study to characterize temporal dynamics of auditory ERPs in ASD, our results provide compelling evidence that heightened response to auditory deviance in ASD is largely driven by early sensitivity and prolonged processing of auditory deviance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.