ArticleThe Annals of thoracic surgery2018
Current State of Empyema Management.
Article in The Annals of thoracic surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03584113 (Video Assisted Thoracoscopic Decortication Versus Interventional Radiology Guided Chest Tube Insertion With Fibrinolytics for the Management of Empyema), which is not on this map. Cited by 61 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Video Assisted Thoracoscopic Decortication Versus Interventional Radiology Guided Chest Tube Insertion With Fibrinolytics for the Management of Empyema (DICE Trial)
Who cites it
61 citing papers in PubMed, 1 synthesis or guideline pooled it, 109 citations in OpenAlex.
- Guidelines for the treatment of empyema (The Japanese Association for Chest Surgery).General thoracic and cardiovascular surgery · 2025Guideline
- Comparing the efficacy of video assisted thoracoscopic surgery (VATS) vs intrapleural fibrinolytic therapy in children with pleural empyema.Pediatric surgery international · 2025Trial
- Effect of Intrapleural Fibrinolytic Therapy vs Surgery for Complicated Pleural Infections: A Randomized Clinical Trial.JAMA network open · 2023Trial
- The Contemporary Utility of the Eloesser Flap for Management of Complex Pleural Space Infections.Annals of thoracic surgery short reports · 2026Article
- Early source control with non-intubated uniportal video-assisted thoracoscopic surgery for acute thoracic empyema: a retrospective pilot cohort study.Journal of thoracic disease · 2026Article
- Focus on pleural empyema: etiology, epidemiology, infectiology, treatment, and impact of the COVID-19 pandemic-a single-center analysis.Journal of thoracic disease · 2026Article
- Intrapleural Gentian Violet Irrigation for Refractory Methicillin-ResistantRespirology case reports · 2026Article
- INHIBITING THE INHIBITOR: WOULD TARGETING PAI-1 RESULT IN A LOW-DOSE, WELL-TOLERATED TREATMENT OF EMPYEMA?Biomedical sciences instrumentation · 2025Article
- Outcomes of adult empyema thoracis cases managed in a tertiary hospital in Uganda: a retrospective cohort study.BMC pulmonary medicine · 2025Article
- Construction of a simulation scenario and a low-cost simulator for teaching thoracentesis procedural technique: a validation study.BMC medical education · 2025Article
- Modified thoracostomy window as a surgical treatment for chronic pleuropulmonary infections.Journal of thoracic disease · 2025Article
- Risk factors and prognostic predictors of recurrent bacterial empyema in patients after surgical treatment.BMC infectious diseases · 2025Article
- Superiority of Surgical Treatment in Stage 2 Acute Empyema: A Perspective on Lung Volume Improvement.Cureus · 2025Article
- Comparison of outcome between sole operation and operation after tube thoracostomy in late phase empyema.Scientific reports · 2025Article
- Rapidly Developing Bilateral Loculated Streptococcus Pyogenes Empyema in an Immunocompetent Adult: A Case Report.Journal of community hospital internal medicine perspectives · 2025Article
- Empyema associated withRespiratory medicine case reports · 2025Article
- Optimal timing for video assisted thoracic surgery decortication for improved survival in chronic empyema.Scientific reports · 2024Observational
- More isn't always better: antibiotic duration after surgical decortication in pleural empyema.Journal of thoracic disease · 2024Article
- Empyema necessitans as a rare manifestation ofClinical case reports · 2024Article
- Evaluation of the RAPID score as a predictor of postoperative morbidity and mortality in patients undergoing pulmonary decortication for stage III pleural empyema.Clinics (Sao Paulo, Brazil) · 2024Article
1 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundEmpyema affects up to 65,000 patients annually in the United States. Recent consensus guidelines demonstrate ambiguity about optimal treatment. We examined current treatment practices and outcomes for inpatient treatment of empyema using a comprehensive, longitudinal data set that encompasses an entire state cohort of hospitalized patients.
methodsWe queried the Healthcare Cost and Utilization Project New York State Inpatient Database (2009 to 2014) for patients with primary empyema and subsequent readmissions. Patients were categorized into three groups by definitive treatment during their initial hospitalization: chest tube drainage, video-assisted thoracoscopic surgery (VATS) decortication and drainage, or open decortication and drainage. Treatment outcomes, including success rates, readmission, reintervention, and mortality, were compared between groups.
resultsThe cohort included 4,095 patients undergoing intervention for primary empyema discharged during this period with chest tube, VATS, or open drainage and decortication. Most patients received definitive operative management (chest tube: 38.2%, VATS: 32.1%, open: 29.8%; p < 0.001). Patients had a high mortality rate during their initial hospitalization (chest tube: 15.4%, VATS: 4.7%, open: 6.0%; p < 0.001) and a substantial 30-day readmission rate for empyema (chest tube: 7.3%, VATS: 3.8%, open: 4.1%; p < 0.001), with reintervention at readmission significantly higher for chest tube (6.1%) vs surgical patients (VATS: 1.9%, open 2.1%; p < 0.001).
conclusionsThis study characterizes recent treatment practices of patients with empyema. Higher readmission and reintervention rates were observed in patients managed with chest tubes, suggesting some of these patients may benefit from earlier definitive surgical intervention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.