Evidence map›Paper›PMID 29549851›Full record

ArticleDrug and alcohol dependence2018

Heterosexual male and female disparities in HIV infection at the end of an epidemic: HIV infection among persons who inject drugs in New York City, 2001-2005 and 2011-2015.

Don C Des Jarlais, Courtney McKnight, Jonathan Feelemyer, Kamyar Arasteh, Susan Tross, Aimee N C Campbell, Hannah L F Cooper, David C Perlman

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Don C Des JarlaisIcahn School of Medicine at Mount Sinai, New York, NY, United States. Electronic address: don.desjarlais@mountsinai.org.
Courtney McKnightIcahn School of Medicine at Mount Sinai, New York, NY, United States.
Jonathan FeelemyerIcahn School of Medicine at Mount Sinai, New York, NY, United States.
Kamyar ArastehIcahn School of Medicine at Mount Sinai, New York, NY, United States.
Susan TrossDepartment of Psychiatry, Columbia University Medical Center and New York State Psychiatric Institute, New York, NY, United States.
Aimee N C CampbellDepartment of Psychiatry, Columbia University Medical Center and New York State Psychiatric Institute, New York, NY, United States.
Hannah L F CooperDepartment of Behavioral Sciences and Health Education, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States.
David C PerlmanIcahn School of Medicine at Mount Sinai, New York, NY, United States.
Icahn School of Medicine at Mount Sinai · USColumbia University Irving Medical Center · USEmory University · USNew York State Psychiatric Institute

Funding

Transdisciplinary Theoretical Svnthesis and Development CoreP30DA011041 · NIDA · NEW YORK UNIVERSITY · PI Holly Hagan, Courtney McKnight · 1998 to 2026
$38.9M
Risk Factors for HIV/AIDS in Drug UsersR01DA003574 · NIDA · NEW YORK UNIVERSITY · PI DES JARLAIS, DON C, MCKNIGHT, COURTNEY · 1986 to 2025
$16.2M
Evaluating ART for All HIV Seropositives: Can it work with the hardest cases?R01DA035707 · NIDA · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI CAMPBELL, AIMEE N, DES JARLAIS, DON C · 2013 to 2017
$3.1M
NIDA NIH HHS P30 DA011041NIDA NIH HHS R01 DA003574NIDA NIH HHS R01 DA035707
6 · The paper itself

Abstract

backgroundWe examined whether sex disparities (heterosexual male:female) in HIV infection continue to persist at the "end of the HIV epidemic" among persons who inject drugs (PWID) in New York City (NYC). An "end of the epidemic" was operationally defined as 1) prevalence of untreated HIV infection <5%, and 2) estimated HIV incidence <0.5/100 person-years.

methodsPWID were recruited from persons entering substance use treatment programs at Mount Sinai Beth Israel in 2001-2005 and 2011-2015. A structured interview was administered, and HIV and HSV-2 testing was conducted. Incidence was estimated using newly diagnosed cases of HIV. Disparity analyses compared prevalence of HIV, of untreated HIV, HIV risk behaviors, and estimated HIV incidence.

resultsBy 2011-2015, both heterosexual male and female PWID met the two criteria for an "end of the epidemic," and there were no significant differences in the prevalence of untreated HIV infection. A large sex difference remained in estimated HIV incidence. In 2013-2015, estimated HIV incidence was 2.8/10,000 PY for males and 7.1/10,000 PY for females. Females had greater risk for HIV on several factors.

conclusionWhile NYC has reached an "end of the epidemic" for both heterosexual male and female PWID, sex disparities persist, particularly differences in HIV incidence. Eliminating the sex disparities may require a greater focus on factors associated with sexual transmission.

Indexed as

EpidemicsHeterosexualitySex CharacteristicsAdultFemaleHIV InfectionsHumansMaleMiddle AgedNew York CitySubstance Abuse, IntravenousSubstance Abuse Treatment CentersYoung AdultHIVInjection drug useNew York citySex/Gender disparities

Identifiers

PMID29549851
PMCPMC6584620
OpenAlexW2790985774

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.