Evidence map›Paper›PMID 29549631›Full record

ArticleJournal of endocrinological investigation2018

Combined BRAF

A Campennì, R M Ruggeri, M Siracusa, S A Pignata, F Di Mauro, A Vento, F Trimarchi, S Baldari

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of endocrinological investigation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

A CampennìDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, Nuclear Medicine Unit, University of Messina, Messina, Italy. acampenni@unime.it.
R M RuggeriDepartment of Clinical and Experimental Medicine, Unit of Endocrinology, University of Messina, Messina, Italy.
M SiracusaDipartimento Servizi Diagnostici, UOC di Medicina Nucleare-ARNAS Civico Di Cristina Benfratelli, Palermo, Italy.
S A PignataDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, Nuclear Medicine Unit, University of Messina, Messina, Italy.
F Di MauroDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, Nuclear Medicine Unit, University of Messina, Messina, Italy.
A VentoDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, Nuclear Medicine Unit, University of Messina, Messina, Italy.
F TrimarchiAccademia Peloritana dei Pericolanti at the University of Messina, Messina, Italy.
S BaldariDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, Nuclear Medicine Unit, University of Messina, Messina, Italy.
University of Messina · ITAzienda di Rilievo Nazionale ed Alta Specializzazione · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of the present study was to evaluate the possible diagnostic role of the combined performance of BRAF mutation analysis and MIBI scintigraphy in papillary thyroid cancer (PTC) patients with incomplete bio-chemical response to first radioiodine therapy (RAIT) performed for thyroid remnant ablation.

methodsThe records of 15 PTC patients with bio-chemical incomplete response to first RAIT were retrospectively analyzed. BRAF

resultsAbnormal radioiodine uptake was found in 10 out of the 15 patients (67%,

conclusionAlbeit obtained in a small retrospective series, our results suggest that the combination of BRAF

Indexed as

Radionuclide ImagingAdultAgedDNA Mutational AnalysisFemaleHumansIodine RadioisotopesMaleMiddle AgedPilot ProjectsProto-Oncogene Proteins B-rafRetrospective StudiesTechnetium Tc 99m SestamibiThyroid NeoplasmsWhole Body ImagingYoung AdultBRAF protein, humanIodine RadioisotopesProto-Oncogene Proteins B-rafTechnetium Tc 99m Sestamibi99mTc-MIBI scintigraphyBio-chemical incomplete responseBRAFV600EMetastatic thyroid cancer

Identifiers

PMID29549631
OpenAlexW2794212842

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.