Evidence map›Paper›PMID 29549549›Full record

ArticleJournal of autism and developmental disorders2018

Maternal Exposures Associated with Autism Spectrum Disorder in Jamaican Children.

MacKinsey A Christian, Maureen Samms-Vaughan, MinJae Lee, Jan Bressler, Manouchehr Hessabi, Megan L Grove, Sydonnie Shakespeare-Pellington, Charlene Coore Desai, Jody-Ann Reece, Katherine A Loveland and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of autism and developmental disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 5 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 5 syntheses or guidelines pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

MacKinsey A ChristianDepartment of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Maureen Samms-VaughanDepartment of Child and Adolescent Health, The University of the West Indies (UWI), Mona Campus, Kingston, Jamaica.
MinJae LeeBiostatistics/Epidemiology/Research Design (BERD) core, Center for Clinical and Translational Sciences (CCTS), The University of Texas Health Science Center at Houston, Houston, TX, USA.
Jan BresslerHuman Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Manouchehr HessabiBiostatistics/Epidemiology/Research Design (BERD) core, Center for Clinical and Translational Sciences (CCTS), The University of Texas Health Science Center at Houston, Houston, TX, USA.
Megan L GroveHuman Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Sydonnie Shakespeare-PellingtonDepartment of Child and Adolescent Health, The University of the West Indies (UWI), Mona Campus, Kingston, Jamaica.
Charlene Coore DesaiDepartment of Child and Adolescent Health, The University of the West Indies (UWI), Mona Campus, Kingston, Jamaica.
Jody-Ann ReeceDepartment of Child and Adolescent Health, The University of the West Indies (UWI), Mona Campus, Kingston, Jamaica.
Katherine A LovelandDepartment of Psychiatry and Behavioral Sciences, The University of Texas McGovern Medical School, Houston, TX, USA.
Eric BoerwinkleHuman Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Mohammad H RahbarDepartment of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA. Mohammad.H.Rahbar@uth.tmc.edu.
The University of Texas Health Science Center at Houston · USUniversity of the West Indies · JMBaylor College of Medicine · US

Funding

Convalescent Plasma to Limit Coronavirus Associated ComplicationsUL1TR003167 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KARP, DANIEL D, MCPHERSON, DAVID D · 2019 to 2023
$45.3M
U OF TEXAS HLTH SCI CTR HOUSTON CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCESUL1RR024148 · NCRR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2006 to 2010
$27.9M
Center for Clinical and Translational Sciences (CCTS)UL1TR000371 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2012 to 2016
$13.4M
Epidemiological Research on Autism in Jamaica - Phase IIR01ES022165 · NIEHS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI RAHBAR, MOHAMMAD HOSSEIN · 2013 to 2018
$2.8M
Epidemiological Research on Autism in JamaicaR21HD057808 · NICHD · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI RAHBAR, MOHAMMAD HOSSEIN · 2009 to 2010
$278k
NCATS NIH HHS UL1 TR000371NCATS NIH HHS UL1 TR003167NCRR NIH HHS UL1 RR024148NICHD NIH HHS R21 HD057808NIEHS NIH HHS R01 ES022165NIH HHS R01ES022165NIH HHS R21HD057808
6 · The paper itself

Abstract

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with poorly understood etiology. Many maternal exposures during pregnancy and breastfeeding potentially interfere with neurodevelopment. Using data from two age- and sex-matched case-control studies in Jamaica (n = 298 pairs), results of conditional logistic regression analyses suggest that maternal exposures to fever or infection (matched odds ratio (MOR) = 3.12, 95% CI 1.74-5.60), physical trauma (MOR 2.02, 95% CI 1.01-4.05), and oil-based paints (MOR 1.99, 95% CI 1.14-3.46) may be associated with ASD. Additionally, maternal exposure to oil-based paints may modify the relationship between maternal exposure to pesticides and ASD, which deepens our understanding of the association between pesticides and ASD.

Indexed as

AdultAutism Spectrum DisorderChildCommunicable DiseasesFemaleHumansJamaicaMaleMaternal ExposurePesticidesPregnancyVolatile Organic CompoundsPesticidesVolatile Organic CompoundsAutism spectrum disorderFeverJamaicaPesticidesPhysical traumaVolatile organic compounds

Identifiers

PMID29549549
PMCPMC6041149
OpenAlexW2791108231

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.