ArticleMycotoxin research2018
Stachybotrychromenes A-C: novel cytotoxic meroterpenoids from Stachybotrys sp.
Article in Mycotoxin research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Characterization of the unconventional meroterpenoid gene cluster from Stachybotrys sp. CPCC 401591 for phenylspirodrimanes biosynthesis.Microbial cell factories · 2025Article
- Phenylspirodrimane with Moderate Reversal Effect of Multidrug Resistance Isolated from the Deep-Sea FungusMolecules (Basel, Switzerland) · 2024Article
- Semisynthetic Approach toward Biologically Active Derivatives of Phenylspirodrimanes fromACS omega · 2022Article
- Review
- Detection of Mycotoxins in Highly Matrix-Loaded House-Dust Samples by QTOF-HRMS, IM-QTOF-HRMS, and TQMS: Advantages and Disadvantages.Analytical chemistry · 2022Article
- Biological activities of meroterpenoids isolated from different sources.Frontiers in pharmacology · 2022Review
- Natural Compounds Isolated fromMolecules (Basel, Switzerland) · 2021Article
- Progress in the Chemistry of Macrocyclic Meroterpenoids.Plants (Basel, Switzerland) · 2020Review
- Chemical Diversity and Biological Activities of Meroterpenoids from Marine Derived-Fungi: A Comprehensive Update.Marine drugs · 2020Review
- Exploring Secondary Metabolite Profiles ofToxins · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the course of gaining new insights into the secondary metabolite profile of various Stachybotrys strains, in particular concerning triprenyl phenol-like compounds, so far, unknown metabolites with analogous structural features were discovered. Three novel meroterpenoids containing a chromene ring moiety, namely stachybotrychromenes A-C, were isolated from solid culture of the filamentous fungus Stachybotrys chartarum DSMZ 12880 (chemotype S). Their structures were elucidated by means of comprehensive spectroscopic analysis (1D and 2D NMR, ESI-HRMS, and CD) as well as by comparison with spectroscopic data of structural analogues described in literature. Stachybotrychromenes A and B exhibited moderate cytotoxic effects on HepG2 cells after 24 h with corresponding IC
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