Observational studyJapanese journal of ophthalmology2018
Risk factors for pterygium recurrence after limbal-conjunctival autografting: a retrospective, single-centre investigation.
Observational study in Japanese journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Amniotic membrane transplantation and conjunctival autograft combined with mitomycin C for the management of primary pterygium: A systematic review and meta-analysis.Frontiers in medicine · 2022Pooled it
- Comparison of postoperative topical interferon-α2b versus intraoperative mitomycin C for pterygium recurrence prevention: a randomized clinical trial.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Trial
- Recurrence rate, time to recurrence, and associated factors after primary pterygium excision with conjunctival-limbal autograft: a prospective cohort study.BMC ophthalmology · 2026Article
- Characteristics and risk factors of recurrent pterygium underwent excision combined with limbal conjunctival autograft in southern rural China.Frontiers in medicine · 2026Article
- Analysis of the application effect of an automated eye position fixation training device in patients undergoing pterygium surgery: a two-year follow-up randomized controlled trial.Frontiers in medicine · 2026Article
- Clinical outcomes of pterygium surgery over a ten-year period: a review of recurrence and complication rates.BMC ophthalmology · 2025Article
- Granzyme B Expression in Conjunctiva of Patients with Pterygium.International journal of molecular sciences · 2024Article
- Accurate detection and grading of pterygium through smartphone by a fusion training model.The British journal of ophthalmology · 2024Article
- Effect of Pterygium Removal Combined with Conjunctival Autograft on Corneal Parameters in Swept-Source Imaging.Journal of clinical medicine · 2022Article
- Characteristics and recurrence of pterygium in Saudi Arabia: a single center study with a long follow-up.BMC ophthalmology · 2021Article
- Bilateral Double-headed Recurrent Pterygium: A Case Presentation and Literature Review.Medical hypothesis, discovery & innovation ophthalmology journal · 2020Article
- Head inversion technique to restore physiological conjunctival structure for surgical treatment of primary pterygium.Scientific reports · 2018Article
- Ologen Implantation versus Conjunctival Autograft Transplantation for Treatment of Pterygium.Journal of ophthalmology · 2018Article
- Recurrent Pterygium: A Review.Journal of current ophthalmologyReview
- Pterygium Recurrence Rates in the Hispanic Population in the Northeastern United States.Journal of current ophthalmologyArticle
- Pterygium: an update on pathophysiology, clinical features, and management.Therapeutic advances in ophthalmologyReview
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine the risk factors related to recurrence of pterygium after pterygium excision with limbal-conjunctival autograft. STUDY
designRetrospective, observational case series.
methodsThe current study included 310 patients who underwent surgical removal of pterygium using limbal-conjunctival autografting. All surgery was performed by the same surgeon at a single Hospital from 2006 to 2011. Preoperative and postoperative patient data were collected. The patients were summoned to follow-up examinations. Procedures with at least 12 months of follow-up were included in the final analysis. Potential risk factors for pterygium recurrence were determined by Cox proportional-hazard linear analysis and recurrence-free survival time was evaluated using Kaplan-Meier method.
resultsThe overall recurrence rate was 5.2% during an average follow-up time of 20.1±8.6 months (range, 12-37 months). According to Kaplan-Meier evaluation, the estimated time to recurrence was 34.2 ± 0.5 months (95% confidence interval 33.3-35.0 months) for the whole population. Multivariate analysis showed that age < 45 years old (RR = 3.582, 95% CI 1.984-13.044, P = 0.047), recurrent type of pterygia (RR = 4.856, 95% CI 1.794-13.142, P = 0.002), and vertical size of pterygium > 6.7 mm (RR = 2.529, 95% CI 1.053-6.075, P = 0.038) were significantly associated with increased risk of recurrence.
conclusionOur findings suggest that young age, recurrent type of pterygia, and larger pterygial tissue are risk factors for pterygium recurrence after surgical excision. Hence, early excision of pterygium is recommended to decrease the recurrence rate.
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