Evidence map›Paper›PMID 29549397›Full record

ArticleInternational journal of public health2018

Early life risk factors and their cumulative effects as predictors of overweight in Spanish children.

Isabel Iguacel, Laura Escartín, Juan M Fernández-Alvira, Iris Iglesia, Idoia Labayen, Luis A Moreno, María Pilar Samper, Gerardo Rodríguez, CALINA study group

Abstract read
PubMed Publisher
In one paragraph

Article in International journal of public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Association of Gestational Age in a Full Range With Childhood Overweight and Obesity: A Systematic Scoping Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Early Risk Factors for Obesity in the First 1000 Days-Relationship with Body Fat and BMI at 2 Years.International journal of environmental research and public health · 2021
    Article
  12. Review
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Isabel IguacelGENUD (Growth, Exercise, NUtrition and Development) Research Group, Faculty of Health Sciences, University of Zaragoza, Spain Edificio del SAI, C/Pedro Cerbuna s/n, 50009, Saragossa, Spain. iguacel@unizar.es.ORCID http://orcid.org/0000-0003-4242-5464
Laura EscartínInstituto de Investigación Sanitaria Aragón (IIS Aragón), Saragossa, Spain.
Juan M Fernández-AlviraGENUD (Growth, Exercise, NUtrition and Development) Research Group, Faculty of Health Sciences, University of Zaragoza, Spain Edificio del SAI, C/Pedro Cerbuna s/n, 50009, Saragossa, Spain.
Iris IglesiaGENUD (Growth, Exercise, NUtrition and Development) Research Group, Faculty of Health Sciences, University of Zaragoza, Spain Edificio del SAI, C/Pedro Cerbuna s/n, 50009, Saragossa, Spain.
Idoia LabayenDepartamento de Nutrición y Bromatología, Universidad del País Vasco, UPV/EHU, Vitoria, Spain.
Luis A MorenoGENUD (Growth, Exercise, NUtrition and Development) Research Group, Faculty of Health Sciences, University of Zaragoza, Spain Edificio del SAI, C/Pedro Cerbuna s/n, 50009, Saragossa, Spain.
María Pilar SamperInstituto de Investigación Sanitaria Aragón (IIS Aragón), Saragossa, Spain.
Gerardo RodríguezGENUD (Growth, Exercise, NUtrition and Development) Research Group, Faculty of Health Sciences, University of Zaragoza, Spain Edificio del SAI, C/Pedro Cerbuna s/n, 50009, Saragossa, Spain.
CALINA study group

Funding

Instituto de Salud Carlos III PI08/0559Instituto de Salud Carlos III PI13/02359Instituto de Salud Carlos III RD12/0026
6 · The paper itself

Abstract

objectivesTo explore early life risk factors of overweight/obesity at age 6 years and their cumulative effects on overweight/obesity at ages 2, 4 and 6 years.

methodsAltogether 1031 Spanish children were evaluated at birth and during a 6-year follow-up. Early life risk factors included: parental overweight/obesity, parental origin/ethnicity, maternal smoking during pregnancy, gestational weight gain, gestational age, birth weight, caesarean section, breastfeeding practices and rapid infant weight gain collected via hospital records. Cumulative effects were assessed by adding up those early risk factors that significantly increased the risk of overweight/obesity. We conducted binary logistic regression models.

resultsRapid infant weight gain (OR 2.29, 99% CI 1.54-3.42), maternal overweight/obesity (OR 1.93, 99% CI 1.27-2.92), paternal overweight/obesity (OR 2.17, 99% CI 1.44-3.28), Latin American/Roma origin (OR 3.20, 99% CI 1.60-6.39) and smoking during pregnancy (OR 1.61, 99% CI 1.01-2.59) remained significant after adjusting for confounders. A higher number of early life risk factors accumulated was associated with overweight/obesity at age 6 years but not at age 2 and 4 years.

conclusionsRapid infant weight gain, parental overweight/obesity, maternal smoking and origin/ethnicity predict childhood overweight/obesity and present cumulative effects. Monitoring children with rapid weight gain and supporting a healthy parental weight are important for childhood obesity prevention.

Indexed as

Birth WeightGestational AgePrenatal Exposure Delayed EffectsBreast FeedingChildChild, PreschoolFemaleHumansLogistic ModelsMalePediatric ObesityPregnancyRisk FactorsChildrenEarly life risk factorsOverweightPregnancyPrevention

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.